EBF4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070231Biological processT cell apoptotic process
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameEBF4
Protein nameTranscription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF-like 4) (O/E-4) (OE-4)
EBF family member 4
EBF4 protein
SynonymsKIAA1442
COE4
DescriptionFUNCTION: Transcription factor . Binds to specific sequence motif 5'-CCCNNG[GA]G-3' in regulatory elements of putative target immunoregulatory genes such as NKG7, GZMA, and TBX21 . Positively modulates transcription of NKG7 . May play a role in regulating FAS/CD95-mediated apoptosis in cytotoxic NK cells and T-cells, probably downstream of interleukin IL2 signaling . .

AccessionsQ8WUY0
ENST00000380648.9
A0A6I8PRX3
E9PEI2
ENST00000449079.7
A0A6I8PL90
ENST00000497450.5
ENST00000469215.2
Q9BQW3
ENST00000609451.6 [Q9BQW3-2]
A0A6I8PR97
A0A0A0MSW2
ENST00000481662.2
Q7Z5T1