E2F5 | OmnibusX

Name	Number of supported studies	Average coverage
B cell	4 studies	23% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of E2F5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	933.93	180 / 180	99%	11.29	426 / 430
brain	99%	412.81	2619 / 2642	98%	8.02	694 / 705
intestine	100%	660.98	966 / 966	96%	7.43	507 / 527
breast	100%	567.93	459 / 459	96%	7.26	1071 / 1118
prostate	100%	779.86	245 / 245	93%	5.36	467 / 502
stomach	100%	480.86	359 / 359	93%	7.10	266 / 286
thymus	100%	1000.49	653 / 653	93%	4.33	562 / 605
lung	100%	614.19	576 / 578	91%	5.54	1048 / 1155
pancreas	100%	389.34	327 / 328	88%	3.44	156 / 178
esophagus	100%	520.50	1444 / 1445	83%	4.62	152 / 183
bladder	100%	537.90	21 / 21	82%	5.38	415 / 504
kidney	100%	645.96	89 / 89	79%	3.03	710 / 901
skin	100%	401.03	1801 / 1809	75%	4.02	352 / 472
uterus	100%	936.83	170 / 170	65%	3.64	298 / 459
adrenal gland	100%	566.74	258 / 258	59%	1.91	135 / 230
liver	100%	298.74	225 / 226	36%	1.68	147 / 406
spleen	100%	958.49	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.52	1 / 1
blood vessel	99%	423.20	1322 / 1335	0%	0	0 / 0
adipose	98%	425.88	1179 / 1204	0%	0	0 / 0
heart	95%	316.84	821 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	11.92	27 / 29
peripheral blood	65%	471.12	608 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	56%	2.29	25 / 45
eye	0%	0	0 / 0	51%	2.62	41 / 80
muscle	37%	62.37	295 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030030	Biological process	cell projection organization
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0009887	Biological process	animal organ morphogenesis
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005730	Cellular component	nucleolus
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0001650	Cellular component	fibrillar center
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005737	Cellular component	cytoplasm
GO_0001216	Molecular function	DNA-binding transcription activator activity
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983	Molecular function	protein dimerization activity
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific

Gene name	E2F5
Protein name	Transcription factor E2F5 (E2F-5) E2F transcription factor 5
Synonyms
Description	FUNCTION: Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. .
Accessions	H0YBK0 ENST00000416274.7 [Q15329-1] H0YBW8 ENST00000520225.1 ENST00000256117.9 ENST00000521429.5 C9JYE9 E5RHD4 Q15329 ENST00000518234.5 ENST00000418930.6 [Q15329-2] ENST00000517476.5 [Q15329-3]

E2F5 report