Name | Number of supported studies | Average coverage | |
---|---|---|---|
kidney loop of Henle epithelial cell | 5 studies | 43% ± 18% | |
placental villous trophoblast | 3 studies | 75% ± 19% |
Insufficient scRNA-seq data for expression of DUSP9 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 90% | 73.89 | 203 / 226 | 70% | 29.62 | 285 / 406 |
brain | 87% | 245.92 | 2297 / 2642 | 66% | 6.32 | 463 / 705 |
ovary | 81% | 103.31 | 146 / 180 | 70% | 7.83 | 302 / 430 |
kidney | 100% | 2916.29 | 89 / 89 | 13% | 2.05 | 116 / 901 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.25 | 1 / 1 |
bladder | 48% | 60.24 | 10 / 21 | 50% | 8.39 | 252 / 504 |
eye | 0% | 0 | 0 / 0 | 95% | 17.85 | 76 / 80 |
esophagus | 31% | 20.59 | 448 / 1445 | 55% | 6.91 | 100 / 183 |
skin | 16% | 5.46 | 293 / 1809 | 54% | 5.32 | 254 / 472 |
uterus | 2% | 1.31 | 4 / 170 | 66% | 12.17 | 302 / 459 |
tonsil | 0% | 0 | 0 / 0 | 60% | 6.67 | 27 / 45 |
lung | 7% | 3.20 | 43 / 578 | 52% | 8.66 | 604 / 1155 |
breast | 27% | 21.00 | 126 / 459 | 19% | 2.00 | 217 / 1118 |
prostate | 24% | 14.98 | 59 / 245 | 0% | 0.01 | 2 / 502 |
adipose | 22% | 12.12 | 262 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 1% | 0.34 | 3 / 258 | 17% | 8.50 | 40 / 230 |
stomach | 1% | 0.45 | 4 / 359 | 16% | 1.81 | 45 / 286 |
intestine | 1% | 0.79 | 14 / 966 | 14% | 0.98 | 73 / 527 |
thymus | 0% | 0.21 | 2 / 653 | 11% | 2.26 | 66 / 605 |
pancreas | 1% | 0.25 | 3 / 328 | 10% | 2.03 | 18 / 178 |
spleen | 6% | 2.12 | 15 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 4% | 1.74 | 49 / 1335 | 0% | 0 | 0 / 0 |
heart | 1% | 0.14 | 5 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.13 | 4 / 929 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.17 | 3 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043409 | Biological process | negative regulation of MAPK cascade |
GO_0007254 | Biological process | JNK cascade |
GO_0070371 | Biological process | ERK1 and ERK2 cascade |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0035335 | Biological process | peptidyl-tyrosine dephosphorylation |
GO_0000165 | Biological process | MAPK cascade |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0017017 | Molecular function | MAP kinase tyrosine/serine/threonine phosphatase activity |
GO_0008330 | Molecular function | protein tyrosine/threonine phosphatase activity |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0033550 | Molecular function | MAP kinase tyrosine phosphatase activity |
GO_0004721 | Molecular function | phosphoprotein phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
Gene name | DUSP9 |
Protein name | Dual specificity protein phosphatase 9 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4) Dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48) |
Synonyms | MKP4 |
Description | FUNCTION: Inactivates MAP kinases. Has a specificity for the ERK family. |
Accessions | Q6P9C2 ENST00000370167.8 ENST00000342782.4 Q99956 |