DSCC1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DSCC1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DSCC1 at tissue level.

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_0034421Biological processpost-translational protein acetylation
GO_0034088Biological processmaintenance of mitotic sister chromatid cohesion
GO_0006275Biological processregulation of DNA replication
GO_0006260Biological processDNA replication
GO_1900264Biological processpositive regulation of DNA-directed DNA polymerase activity
GO_0000775Cellular componentchromosome, centromeric region
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0031390Cellular componentCtf18 RFC-like complex
GO_0003677Molecular functionDNA binding
GO_0003689Molecular functionDNA clamp loader activity
GO_0005515Molecular functionprotein binding
GO_0017116Molecular functionsingle-stranded DNA helicase activity

IV. Literature review

[source]
Gene nameDSCC1
Protein nameSister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog)
SynonymsUNQ9337/PRO34008
DCC1
DescriptionFUNCTION: Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3. .

AccessionsENST00000313655.5
Q9BVC3