Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| non-classical monocyte | 3 studies | 21% ± 5% | |
| epithelial cell | 3 studies | 32% ± 7% | |
| ciliated cell | 3 studies | 18% ± 1% | |
| dendritic cell | 3 studies | 27% ± 7% | |
| natural killer cell | 3 studies | 16% ± 1% |
Insufficient scRNA-seq data for expression of DRG2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1562.58 | 1445 / 1445 | 100% | 9.99 | 183 / 183 |
| pancreas | 100% | 965.99 | 328 / 328 | 100% | 8.82 | 178 / 178 |
| prostate | 100% | 2008.15 | 245 / 245 | 100% | 14.56 | 502 / 502 |
| skin | 100% | 1685.90 | 1809 / 1809 | 100% | 12.09 | 472 / 472 |
| stomach | 100% | 1188.61 | 359 / 359 | 100% | 9.71 | 286 / 286 |
| lung | 100% | 1441.72 | 578 / 578 | 100% | 10.65 | 1154 / 1155 |
| breast | 100% | 1720.33 | 459 / 459 | 100% | 10.96 | 1116 / 1118 |
| intestine | 100% | 1528.45 | 966 / 966 | 100% | 10.07 | 526 / 527 |
| ovary | 100% | 1832.41 | 180 / 180 | 100% | 8.11 | 429 / 430 |
| thymus | 100% | 1834.70 | 653 / 653 | 100% | 13.00 | 603 / 605 |
| bladder | 100% | 1607.05 | 21 / 21 | 100% | 11.43 | 502 / 504 |
| brain | 100% | 1089.02 | 2629 / 2642 | 100% | 10.90 | 703 / 705 |
| kidney | 100% | 1381.88 | 89 / 89 | 99% | 10.08 | 894 / 901 |
| liver | 100% | 890.65 | 226 / 226 | 99% | 8.11 | 402 / 406 |
| uterus | 100% | 1979.28 | 170 / 170 | 99% | 11.47 | 454 / 459 |
| adrenal gland | 100% | 1571.71 | 258 / 258 | 97% | 7.76 | 223 / 230 |
| adipose | 100% | 1537.14 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 15.01 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.30 | 29 / 29 |
| muscle | 100% | 1587.19 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1974.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.37 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.38 | 1 / 1 |
| blood vessel | 100% | 1466.24 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 970.08 | 854 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1097.84 | 907 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0002181 | Biological process | cytoplasmic translation |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005525 | Molecular function | GTP binding |
| GO_0003924 | Molecular function | GTPase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | DRG2 |
| Protein name | Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) Developmentally regulated GTP binding protein 2 |
| Synonyms | |
| Description | FUNCTION: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. . |
| Accessions | ENST00000577450.5 J3QLF3 J3QQI1 ENST00000580929.5 J3QRI9 J3KRL5 ENST00000467099.6 J3QL90 ENST00000580055.5 J3QR71 ENST00000582314.5 ENST00000579601.5 ENST00000582419.5 J3QKW7 ENST00000579224.5 ENST00000395726.8 ENST00000496428.6 A8MZF9 ENST00000225729.8 P55039 ENST00000583355.1 J3QKV7 |