I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 18 studies | 64% ± 13% | |
| deuterosomal cell | 4 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 18 studies | 64% ± 13% | |
| deuterosomal cell | 4 studies | 22% ± 3% |
Insufficient scRNA-seq data for expression of DRC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 1153.97 | 653 / 653 | 98% | 5.32 | 595 / 605 |
| prostate | 100% | 390.19 | 245 / 245 | 97% | 2.42 | 485 / 502 |
| brain | 94% | 292.06 | 2495 / 2642 | 99% | 5.08 | 701 / 705 |
| kidney | 100% | 489.97 | 89 / 89 | 91% | 5.31 | 820 / 901 |
| ovary | 100% | 381.42 | 180 / 180 | 80% | 2.41 | 346 / 430 |
| breast | 95% | 276.58 | 438 / 459 | 85% | 3.70 | 950 / 1118 |
| pancreas | 98% | 172.45 | 322 / 328 | 80% | 1.82 | 143 / 178 |
| adrenal gland | 98% | 155.58 | 252 / 258 | 77% | 2.04 | 176 / 230 |
| esophagus | 90% | 120.75 | 1297 / 1445 | 76% | 1.41 | 139 / 183 |
| lung | 98% | 643.53 | 565 / 578 | 67% | 1.84 | 772 / 1155 |
| uterus | 100% | 526.00 | 170 / 170 | 62% | 1.67 | 284 / 459 |
| skin | 85% | 142.72 | 1544 / 1809 | 68% | 1.44 | 320 / 472 |
| bladder | 86% | 132.19 | 18 / 21 | 39% | 0.69 | 195 / 504 |
| intestine | 91% | 139.24 | 876 / 966 | 30% | 0.48 | 159 / 527 |
| stomach | 79% | 105.00 | 284 / 359 | 39% | 0.61 | 111 / 286 |
| spleen | 100% | 198.60 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 92% | 117.38 | 1227 / 1335 | 0% | 0 | 0 / 0 |
| liver | 68% | 69.35 | 154 / 226 | 22% | 0.56 | 90 / 406 |
| adipose | 87% | 124.09 | 1052 / 1204 | 0% | 0 | 0 / 0 |
| heart | 81% | 99.87 | 698 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 78% | 1.53 | 62 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 1.25 | 26 / 45 |
| muscle | 57% | 56.32 | 455 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 0.53 | 9 / 29 |
| peripheral blood | 1% | 1.96 | 8 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005930 | Cellular component | axoneme |
| GO_0005929 | Cellular component | cilium |
| GO_0036126 | Cellular component | sperm flagellum |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DRC3 |
| Protein name | Dynein regulatory complex subunit 3 Alternative protein LRRC48 Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48) |
| Synonyms | LRRC48 |
| Description | FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. . |
| Accessions | ENST00000585108.5 J3KRN8 ENST00000479684.2 J3QSG4 ENST00000399187.6 [Q9H069-1] ENST00000581264.5 ENST00000579376.1 L8E869 ENST00000583171.5 K7EJT6 Q9H069 ENST00000579977.1 ENST00000496293.2 ENST00000582416.5 J3QRC9 J3QS14 J3QRH8 J3KRB8 J3QR90 ENST00000399182.5 [Q9H069-2] ENST00000584166.5 [Q9H069-2] |
