Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 31 studies | 31% ± 12% | |
pericyte | 18 studies | 24% ± 8% | |
endothelial cell of lymphatic vessel | 10 studies | 33% ± 17% | |
capillary endothelial cell | 10 studies | 25% ± 7% | |
endothelial cell of artery | 6 studies | 23% ± 4% | |
fibroblast | 6 studies | 18% ± 2% | |
adipocyte | 5 studies | 19% ± 3% | |
vein endothelial cell | 4 studies | 26% ± 11% | |
endothelial cell of vascular tree | 4 studies | 33% ± 17% | |
glomerular endothelial cell | 3 studies | 22% ± 2% | |
epithelial cell | 3 studies | 26% ± 13% | |
astrocyte | 3 studies | 18% ± 2% |
Insufficient scRNA-seq data for expression of DOCK6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4684.89 | 1445 / 1445 | 100% | 25.92 | 183 / 183 |
intestine | 100% | 4538.87 | 966 / 966 | 100% | 21.07 | 525 / 527 |
uterus | 100% | 5119.74 | 170 / 170 | 99% | 13.19 | 456 / 459 |
stomach | 100% | 3562.53 | 359 / 359 | 99% | 21.45 | 284 / 286 |
bladder | 100% | 4255.48 | 21 / 21 | 99% | 14.84 | 498 / 504 |
lung | 100% | 14231.02 | 578 / 578 | 99% | 13.78 | 1139 / 1155 |
prostate | 100% | 4937.82 | 245 / 245 | 99% | 8.06 | 495 / 502 |
thymus | 100% | 9363.73 | 653 / 653 | 98% | 20.13 | 594 / 605 |
kidney | 100% | 6779.08 | 89 / 89 | 98% | 18.40 | 883 / 901 |
breast | 100% | 8527.57 | 459 / 459 | 97% | 10.15 | 1090 / 1118 |
pancreas | 98% | 2226.31 | 320 / 328 | 99% | 17.30 | 176 / 178 |
skin | 100% | 5474.22 | 1802 / 1809 | 97% | 10.98 | 456 / 472 |
adrenal gland | 100% | 2971.16 | 258 / 258 | 91% | 9.57 | 209 / 230 |
liver | 96% | 2317.23 | 218 / 226 | 93% | 7.74 | 379 / 406 |
ovary | 100% | 3557.30 | 180 / 180 | 88% | 8.17 | 378 / 430 |
brain | 63% | 1015.77 | 1668 / 2642 | 93% | 7.87 | 657 / 705 |
adipose | 100% | 8990.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 10.91 | 80 / 80 |
spleen | 100% | 4471.43 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 11.58 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.21 | 1 / 1 |
heart | 100% | 4474.44 | 859 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3573.75 | 1329 / 1335 | 0% | 0 | 0 / 0 |
muscle | 88% | 1535.66 | 706 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 5.11 | 24 / 29 |
peripheral blood | 16% | 327.99 | 146 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007264 | Biological process | small GTPase-mediated signal transduction |
GO_0005829 | Cellular component | cytosol |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DOCK6 |
Protein name | Dedicator of cytokinesis 6 Dedicator of cytokinesis protein 6 DOCK6 |
Synonyms | KIAA1395 |
Description | FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity). . |
Accessions | ENST00000585904.1 K7EP51 K7ERK2 K7EP20 ENST00000590680.5 K7ESB7 A0A2X0TVX1 ENST00000294618.12 Q96HP0 ENST00000587734.1 K7EKT0 ENST00000587656.6 ENST00000588666.1 |