DOCK6 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DOCK6 at tissue level.

III. Associated gene sets

GO_0043547Biological processpositive regulation of GTPase activity
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0005829Cellular componentcytosol
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDOCK6
Protein nameDedicator of cytokinesis 6
Dedicator of cytokinesis protein 6
DOCK6
SynonymsKIAA1395
DescriptionFUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity). .

AccessionsENST00000585904.1
K7EP51
K7ERK2
K7EP20
ENST00000590680.5
K7ESB7
A0A2X0TVX1
ENST00000294618.12
Q96HP0
ENST00000587734.1
K7EKT0
ENST00000587656.6
ENST00000588666.1