DNAJC13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000641Biological processregulation of early endosome to late endosome transport
GO_0015031Biological processprotein transport
GO_1902954Biological processregulation of early endosome to recycling endosome transport
GO_0006898Biological processreceptor-mediated endocytosis
GO_0007032Biological processendosome organization
GO_0001649Biological processosteoblast differentiation
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0010008Cellular componentendosome membrane
GO_0031901Cellular componentearly endosome membrane
GO_0030667Cellular componentsecretory granule membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0070062Cellular componentextracellular exosome
GO_0071203Cellular componentWASH complex
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005765Cellular componentlysosomal membrane
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDNAJC13
Protein nameDnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)
DNAJC13 protein
DnaJ heat shock protein family (Hsp40) member C13
SynonymsRME8
KIAA0678
DescriptionFUNCTION: Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR . Involved in the regulation of endosomal membrane tubulation and regulates the dynamics of SNX1 on the endosomal membrane; via association with WASHC2 may link the WASH complex to the retromer SNX-BAR subcomplex . .

AccessionsENST00000260818.11
H0YA63
O75165
ENST00000509279.1
ENST00000650455.1
A0A3B3IRM0
H0Y8Q2
Q0D2M7
ENST00000506813.1