I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 29% ± 13% | |
| retinal ganglion cell | 4 studies | 56% ± 29% | |
| neuron | 3 studies | 23% ± 6% | |
| GABAergic neuron | 3 studies | 31% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 29% ± 13% | |
| retinal ganglion cell | 4 studies | 56% ± 29% | |
| neuron | 3 studies | 23% ± 6% | |
| GABAergic neuron | 3 studies | 31% ± 4% |
Insufficient scRNA-seq data for expression of DIRAS1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 6349.52 | 2510 / 2642 | 100% | 67.30 | 703 / 705 |
| prostate | 33% | 348.79 | 82 / 245 | 95% | 13.50 | 477 / 502 |
| skin | 26% | 280.08 | 467 / 1809 | 93% | 46.13 | 437 / 472 |
| uterus | 90% | 1874.29 | 153 / 170 | 19% | 8.21 | 86 / 459 |
| eye | 0% | 0 | 0 / 0 | 100% | 70.88 | 80 / 80 |
| heart | 98% | 9788.40 | 842 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 63% | 1121.22 | 911 / 1445 | 19% | 2.83 | 35 / 183 |
| breast | 13% | 105.93 | 59 / 459 | 69% | 14.15 | 769 / 1118 |
| adrenal gland | 5% | 45.02 | 14 / 258 | 75% | 34.27 | 172 / 230 |
| bladder | 38% | 473.05 | 8 / 21 | 12% | 1.74 | 61 / 504 |
| kidney | 26% | 226.80 | 23 / 89 | 18% | 3.91 | 162 / 901 |
| ovary | 27% | 237.47 | 48 / 180 | 16% | 1.76 | 69 / 430 |
| pancreas | 22% | 203.15 | 72 / 328 | 18% | 4.36 | 32 / 178 |
| spleen | 39% | 468.22 | 95 / 241 | 0% | 0 | 0 / 0 |
| lung | 0% | 19.64 | 1 / 578 | 28% | 4.43 | 324 / 1155 |
| stomach | 20% | 159.86 | 71 / 359 | 7% | 1.43 | 21 / 286 |
| intestine | 6% | 52.74 | 58 / 966 | 5% | 0.56 | 25 / 527 |
| thymus | 0% | 5.26 | 3 / 653 | 10% | 0.92 | 62 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 2.05 | 4 / 45 |
| liver | 0% | 0 | 0 / 226 | 8% | 1.15 | 34 / 406 |
| muscle | 8% | 92.85 | 66 / 803 | 0% | 0 | 0 / 0 |
| adipose | 5% | 48.34 | 62 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.33 | 1 / 29 |
| blood vessel | 3% | 37.10 | 37 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 3.43 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043406 | Biological process | positive regulation of MAP kinase activity |
| GO_0007165 | Biological process | signal transduction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0051019 | Molecular function | mitogen-activated protein kinase binding |
| GO_0019003 | Molecular function | GDP binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | DIRAS1 |
| Protein name | DIRAS family GTPase 1 GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1) |
| Synonyms | GBTS1 RIG |
| Description | FUNCTION: Displays low GTPase activity and exists predominantly in the GTP-bound form. . |
| Accessions | ENST00000323469.5 O95057 K7EN06 ENST00000588128.1 ENST00000585334.1 |
