DHX30 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_1902775Biological processmitochondrial large ribosomal subunit assembly
GO_0007417Biological processcentral nervous system development
GO_0005622Cellular componentintracellular anatomical structure
GO_0042645Cellular componentmitochondrial nucleoid
GO_0005739Cellular componentmitochondrion
GO_0035770Cellular componentribonucleoprotein granule
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003724Molecular functionRNA helicase activity
GO_0003682Molecular functionchromatin binding
GO_0003678Molecular functionDNA helicase activity
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0002151Molecular functionG-quadruplex RNA binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0003725Molecular functiondouble-stranded RNA binding

IV. Literature review

[source]
Gene nameDHX30
Protein nameDExH-box helicase 30
ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30)
SynonymsKIAA0890
DDX30
DescriptionFUNCTION: RNA-dependent helicase . Plays an important role in the assembly of the mitochondrial large ribosomal subunit . Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA . Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (By similarity). .

AccessionsQ7L2E3
ENST00000395745.6
ENST00000619982.4 [Q7L2E3-3]
ENST00000348968.8
ENST00000457607.1 [Q7L2E3-2]
F6R0H4
ENST00000415400.5
ENST00000445061.6 [Q7L2E3-1]
ENST00000446256.6 [Q7L2E3-1]
ENST00000441384.5
H7BXY3