DHX29 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001731Biological processformation of translation preinitiation complex
GO_0045948Biological processpositive regulation of translational initiation
GO_0042255Biological processribosome assembly
GO_0005622Cellular componentintracellular anatomical structure
GO_0016282Cellular componenteukaryotic 43S preinitiation complex
GO_0022627Cellular componentcytosolic small ribosomal subunit
GO_0003743Molecular functiontranslation initiation factor activity
GO_0045296Molecular functioncadherin binding
GO_0004386Molecular functionhelicase activity
GO_0043024Molecular functionribosomal small subunit binding
GO_0008494Molecular functiontranslation activator activity
GO_0003724Molecular functionRNA helicase activity
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0017111Molecular functionribonucleoside triphosphate phosphatase activity

IV. Literature review

[source]
Gene nameDHX29
Protein nameDExH-box helicase 29
ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx)
SynonymsDDX29
DescriptionFUNCTION: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. .

AccessionsH0Y8L1
Q7Z478
ENST00000508346.1
ENST00000251636.10