DFFB | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	3 studies	30% ± 5%	Explore
glutamatergic neuron	3 studies	33% ± 6%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	778.12	2622 / 2642	99%	6.43	701 / 705
intestine	100%	720.75	966 / 966	98%	10.59	519 / 527
bladder	100%	648.43	21 / 21	98%	7.27	495 / 504
ovary	100%	969.73	180 / 180	98%	6.90	422 / 430
breast	100%	536.30	459 / 459	98%	6.11	1097 / 1118
stomach	99%	518.13	357 / 359	99%	9.54	282 / 286
thymus	100%	708.05	653 / 653	97%	5.45	589 / 605
prostate	100%	727.30	245 / 245	97%	5.87	488 / 502
lung	98%	527.06	569 / 578	99%	5.82	1140 / 1155
pancreas	100%	584.66	328 / 328	97%	6.09	172 / 178
uterus	100%	849.18	170 / 170	97%	6.02	443 / 459
skin	98%	369.49	1776 / 1809	98%	7.14	462 / 472
esophagus	100%	465.06	1440 / 1445	93%	5.73	170 / 183
kidney	100%	544.71	89 / 89	82%	3.50	736 / 901
adrenal gland	100%	486.57	257 / 258	68%	2.36	157 / 230
liver	100%	426.13	226 / 226	46%	1.60	188 / 406
spleen	100%	1097.83	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.36	1 / 1
adipose	100%	496.29	1201 / 1204	0%	0	0 / 0
blood vessel	99%	417.10	1327 / 1335	0%	0	0 / 0
heart	98%	318.34	844 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	5.50	42 / 45
lymph node	0%	0	0 / 0	90%	5.99	26 / 29
muscle	87%	179.71	700 / 803	0%	0	0 / 0
peripheral blood	85%	336.94	794 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	71%	3.14	57 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006308	Biological process	DNA catabolic process
GO_0006309	Biological process	apoptotic DNA fragmentation
GO_1902511	Biological process	negative regulation of apoptotic DNA fragmentation
GO_0030263	Biological process	apoptotic chromosome condensation
GO_0005730	Cellular component	nucleolus
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0019899	Molecular function	enzyme binding
GO_0004536	Molecular function	DNA nuclease activity
GO_0019904	Molecular function	protein domain specific binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0097718	Molecular function	disordered domain specific binding
GO_0004520	Molecular function	DNA endonuclease activity

Gene name	DFFB
Protein name	DNA fragmentation factor subunit beta (DNAation factor B truncated form III) DFFB protein (DNA fragmentation factor subunit beta) (DNAation factor B truncated form II) (DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_d) DNA fragmentation factor subunit beta DNA fragmentation factor subunit beta (DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_a) DNA fragmentation factor subunit beta (EC 3.-.-.-) (Caspase-activated deoxyribonuclease) (CAD) (Caspase-activated DNase) (Caspase-activated nuclease) (CPAN) (DNA fragmentation factor 40 kDa subunit) (DFF-40) DNAation factor B truncated form I DNA fragmentation factor subunit beta (cDNA FLJ50316, highly similar to DNAation factor subunit beta)
Synonyms	hCG_31570 DFF40 DFF2 CAD
Description	FUNCTION: Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
Accessions	Q96P73 J3KT26 ENST00000475969.5 ENST00000477548.5 ENST00000378206.5 ENST00000491998.5 [O76075-2] ENST00000339350.7 [O76075-3] Q96P74 Q96P72 O76075 ENST00000378209.8 [O76075-1] ENST00000468793.5 ENST00000338895.7 B4DZS0 ENST00000625756.2 G3XAD0 ENST00000461150.1

DFFB report