Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 23 studies | 29% ± 13% | |
oligodendrocyte | 17 studies | 46% ± 18% | |
astrocyte | 15 studies | 33% ± 12% | |
oligodendrocyte precursor cell | 13 studies | 44% ± 17% | |
macrophage | 13 studies | 32% ± 14% | |
fibroblast | 12 studies | 27% ± 12% | |
microglial cell | 11 studies | 37% ± 12% | |
GABAergic neuron | 10 studies | 38% ± 22% | |
pericyte | 10 studies | 30% ± 12% | |
myeloid cell | 9 studies | 28% ± 9% | |
classical monocyte | 8 studies | 26% ± 9% | |
non-classical monocyte | 8 studies | 25% ± 10% | |
adipocyte | 8 studies | 21% ± 5% | |
monocyte | 7 studies | 37% ± 13% | |
interneuron | 6 studies | 41% ± 20% | |
retinal cone cell | 6 studies | 28% ± 8% | |
dendritic cell | 6 studies | 27% ± 5% | |
smooth muscle cell | 6 studies | 26% ± 8% | |
neuron | 5 studies | 34% ± 19% | |
glutamatergic neuron | 5 studies | 53% ± 21% | |
cardiac muscle cell | 5 studies | 24% ± 4% | |
endothelial cell of lymphatic vessel | 5 studies | 27% ± 10% | |
neutrophil | 4 studies | 24% ± 7% | |
granule cell | 4 studies | 20% ± 4% | |
Mueller cell | 4 studies | 19% ± 3% | |
endothelial cell of vascular tree | 4 studies | 29% ± 24% | |
alveolar macrophage | 4 studies | 45% ± 18% | |
GABAergic interneuron | 3 studies | 27% ± 3% | |
vein endothelial cell | 3 studies | 39% ± 23% | |
epithelial cell | 3 studies | 32% ± 17% | |
type I pneumocyte | 3 studies | 18% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 10775.34 | 2642 / 2642 | 100% | 135.32 | 704 / 705 |
breast | 100% | 6831.93 | 459 / 459 | 99% | 31.48 | 1109 / 1118 |
prostate | 100% | 5027.71 | 244 / 245 | 98% | 21.50 | 493 / 502 |
kidney | 100% | 3483.37 | 89 / 89 | 98% | 34.72 | 881 / 901 |
thymus | 100% | 4580.16 | 651 / 653 | 98% | 22.65 | 593 / 605 |
lung | 100% | 7902.28 | 577 / 578 | 97% | 25.52 | 1123 / 1155 |
ovary | 100% | 5143.16 | 180 / 180 | 96% | 17.30 | 411 / 430 |
skin | 96% | 4497.09 | 1744 / 1809 | 99% | 41.19 | 468 / 472 |
adrenal gland | 100% | 4173.57 | 258 / 258 | 92% | 17.96 | 211 / 230 |
uterus | 100% | 7466.30 | 170 / 170 | 92% | 20.47 | 421 / 459 |
bladder | 100% | 7401.43 | 21 / 21 | 89% | 15.11 | 450 / 504 |
pancreas | 91% | 2295.18 | 297 / 328 | 95% | 19.93 | 169 / 178 |
esophagus | 95% | 5788.49 | 1366 / 1445 | 90% | 19.35 | 165 / 183 |
stomach | 95% | 3650.78 | 341 / 359 | 78% | 12.58 | 224 / 286 |
intestine | 94% | 5860.57 | 908 / 966 | 73% | 10.46 | 387 / 527 |
liver | 58% | 1140.14 | 130 / 226 | 82% | 12.31 | 332 / 406 |
adipose | 100% | 8068.27 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 5924.32 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.65 | 1 / 1 |
blood vessel | 100% | 8276.23 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 6400.65 | 856 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 8254.72 | 916 / 929 | 0% | 0 | 0 / 0 |
muscle | 97% | 2614.23 | 781 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 20.59 | 43 / 45 |
eye | 0% | 0 | 0 / 0 | 95% | 19.45 | 76 / 80 |
lymph node | 0% | 0 | 0 / 0 | 79% | 17.06 | 23 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
GO_0010977 | Biological process | negative regulation of neuron projection development |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0030904 | Cellular component | retromer complex |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
Gene name | DENND5A |
Protein name | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) DENN domain containing 5A (cDNA FLJ58453, highly similar to Rab6-interacting protein 1) DENN domain containing 5A (RAB6 interacting protein 1, isoform CRA_b) DENN domain containing 5A |
Synonyms | hCG_1810916 RAB6IP1 KIAA1091 |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). . |
Accessions | ENST00000527896.1 H0YEA8 H0YCW5 ENST00000528725.5 A0A7P0TAA7 ENST00000680470.1 ENST00000328194.8 [Q6IQ26-1] A0A7P0TAF6 ENST00000679999.1 ENST00000680742.1 A0A7P0T9H0 ENST00000524446.2 ENST00000533737.5 ENST00000530780.2 A0A7P0T8L1 H0YDS8 ENST00000680252.1 A0A7P0T8L8 A0A7P0T9Z2 A0A7P0Z4N9 B4DFB6 ENST00000530044.5 [Q6IQ26-2] ENST00000681158.1 ENST00000679568.1 Q6IQ26 ENST00000680554.1 A0A7P0TAH5 E9PIS3 ENST00000680294.1 ENST00000526707.5 H0YDV6 ENST00000681203.1 |