DENND5A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0010977Biological processnegative regulation of neuron projection development
GO_0005802Cellular componenttrans-Golgi network
GO_0030904Cellular componentretromer complex
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding

IV. Literature review

[source]
Gene nameDENND5A
Protein nameDENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)
DENN domain containing 5A (cDNA FLJ58453, highly similar to Rab6-interacting protein 1)
DENN domain containing 5A (RAB6 interacting protein 1, isoform CRA_b)
DENN domain containing 5A
SynonymshCG_1810916
RAB6IP1
KIAA1091
DescriptionFUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). .

AccessionsENST00000527896.1
H0YEA8
H0YCW5
ENST00000528725.5
A0A7P0TAA7
ENST00000680470.1
ENST00000328194.8 [Q6IQ26-1]
A0A7P0TAF6
ENST00000679999.1
ENST00000680742.1
A0A7P0T9H0
ENST00000524446.2
ENST00000533737.5
ENST00000530780.2
A0A7P0T8L1
H0YDS8
ENST00000680252.1
A0A7P0T8L8
A0A7P0T9Z2
A0A7P0Z4N9
B4DFB6
ENST00000530044.5 [Q6IQ26-2]
ENST00000681158.1
ENST00000679568.1
Q6IQ26
ENST00000680554.1
A0A7P0TAH5
E9PIS3
ENST00000680294.1
ENST00000526707.5
H0YDV6
ENST00000681203.1