Insufficient scRNA-seq data for expression of DDN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 67% | 16038.93 | 1767 / 2642 | 90% | 27.91 | 635 / 705 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.03 | 1 / 1 |
muscle | 96% | 27416.08 | 770 / 803 | 0% | 0 | 0 / 0 |
kidney | 60% | 2254.89 | 53 / 89 | 3% | 0.15 | 27 / 901 |
intestine | 0% | 0 | 0 / 966 | 58% | 2.12 | 304 / 527 |
lymph node | 0% | 0 | 0 / 0 | 48% | 2.16 | 14 / 29 |
adrenal gland | 0% | 0 | 0 / 258 | 46% | 1.53 | 105 / 230 |
stomach | 0% | 0 | 0 / 359 | 44% | 1.55 | 125 / 286 |
esophagus | 0% | 7.09 | 3 / 1445 | 36% | 0.83 | 66 / 183 |
tonsil | 0% | 0 | 0 / 0 | 31% | 3.62 | 14 / 45 |
bladder | 0% | 0 | 0 / 21 | 30% | 0.80 | 150 / 504 |
uterus | 0% | 0 | 0 / 170 | 25% | 1.53 | 115 / 459 |
lung | 0% | 0 | 0 / 578 | 24% | 0.66 | 280 / 1155 |
skin | 0% | 8.15 | 1 / 1809 | 24% | 0.87 | 114 / 472 |
prostate | 4% | 107.14 | 10 / 245 | 8% | 0.85 | 39 / 502 |
breast | 0% | 0 | 0 / 459 | 10% | 0.31 | 110 / 1118 |
ovary | 0% | 0 | 0 / 180 | 6% | 0.14 | 27 / 430 |
pancreas | 0% | 0 | 0 / 328 | 4% | 0.17 | 7 / 178 |
eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
liver | 0% | 0 | 0 / 226 | 2% | 0.04 | 9 / 406 |
thymus | 0% | 0 | 0 / 653 | 1% | 0.06 | 6 / 605 |
peripheral blood | 1% | 10.66 | 6 / 929 | 0% | 0 | 0 / 0 |
adipose | 0% | 2.16 | 1 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 4.03 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0042995 | Cellular component | cell projection |
GO_0043204 | Cellular component | perikaryon |
GO_0005737 | Cellular component | cytoplasm |
GO_0032591 | Cellular component | dendritic spine membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | DDN |
Protein name | Dendrin |
Synonyms | KIAA0749 |
Description | FUNCTION: Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity). . |
Accessions | B9EGD7 ENST00000421952.3 O94850 |