DDN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DDN at tissue level.

III. Associated gene sets

GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0042995Cellular componentcell projection
GO_0043204Cellular componentperikaryon
GO_0005737Cellular componentcytoplasm
GO_0032591Cellular componentdendritic spine membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameDDN
Protein nameDendrin
SynonymsKIAA0749
DescriptionFUNCTION: Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity). .

AccessionsB9EGD7
ENST00000421952.3
O94850