DCUN1D5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000434Biological processregulation of protein neddylation
GO_2000436Biological processpositive regulation of protein neddylation
GO_0006974Biological processDNA damage response
GO_0045116Biological processprotein neddylation
GO_0001558Biological processregulation of cell growth
GO_0000151Cellular componentubiquitin ligase complex
GO_0005819Cellular componentspindle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0031624Molecular functionubiquitin conjugating enzyme binding
GO_0097602Molecular functioncullin family protein binding
GO_0005515Molecular functionprotein binding
GO_0032182Molecular functionubiquitin-like protein binding

IV. Literature review

[source]
Gene nameDCUN1D5
Protein nameDCN1-like protein 5 (DCNL5) (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5) (Squamous cell carcinoma-related oncogene 5)
DCN1-like protein (Defective in cullin neddylation protein 1-like protein)
Defective in cullin neddylation 1 domain containing 5
SynonymsSCCRO5
DescriptionFUNCTION: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) . May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth . .

AccessionsE9PLH8
ENST00000260247.10
E9PLS2
ENST00000531571.5
ENST00000583974.1
ENST00000527576.5
E9PM04
E9PQV9
ENST00000527779.1
ENST00000529281.5
Q9BTE7
E9PM78
J3QQL8
ENST00000531543.1
H0YCN4
ENST00000529294.5
ENST00000525420.1
ENST00000527260.5
H0YD80