DBX1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DBX1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DBX1 at tissue level.

III. Associated gene sets

GO_0021515Biological processcell differentiation in spinal cord
GO_0021521Biological processventral spinal cord interneuron specification
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameDBX1
Protein nameHomeobox protein DBX1 (Developing brain homeobox protein 1)
Synonyms
DescriptionFUNCTION: Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity). .

AccessionsENST00000524983.3
A6NMT0