Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 11 studies | 42% ± 11% | |
| interneuron | 6 studies | 41% ± 16% | |
| GABAergic neuron | 6 studies | 38% ± 11% | |
| hepatocyte | 4 studies | 64% ± 17% | |
| neuron | 4 studies | 30% ± 19% | |
| oligodendrocyte precursor cell | 4 studies | 28% ± 6% | |
| retina horizontal cell | 4 studies | 54% ± 9% | |
| cholangiocyte | 3 studies | 27% ± 3% | |
| endothelial cell | 3 studies | 41% ± 17% | |
| GABAergic amacrine cell | 3 studies | 40% ± 8% | |
| amacrine cell | 3 studies | 30% ± 5% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 95% | 2547.20 | 233 / 245 | 99% | 40.10 | 498 / 502 |
| liver | 100% | 3476.39 | 226 / 226 | 77% | 13.86 | 311 / 406 |
| brain | 86% | 1100.12 | 2270 / 2642 | 63% | 8.10 | 441 / 705 |
| thymus | 95% | 809.95 | 619 / 653 | 15% | 2.12 | 90 / 605 |
| stomach | 70% | 372.47 | 250 / 359 | 1% | 0.06 | 2 / 286 |
| intestine | 46% | 73.32 | 447 / 966 | 1% | 0.03 | 3 / 527 |
| breast | 37% | 224.29 | 169 / 459 | 10% | 0.94 | 108 / 1118 |
| skin | 22% | 42.00 | 396 / 1809 | 2% | 0.15 | 8 / 472 |
| uterus | 3% | 8.99 | 5 / 170 | 8% | 0.47 | 37 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.32 | 3 / 29 |
| muscle | 10% | 17.57 | 79 / 803 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 7% | 0.81 | 32 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.22 | 3 / 45 |
| kidney | 4% | 8.15 | 4 / 89 | 1% | 0.13 | 6 / 901 |
| esophagus | 0% | 0.16 | 2 / 1445 | 5% | 0.28 | 9 / 183 |
| pancreas | 2% | 2.04 | 6 / 328 | 1% | 0.42 | 2 / 178 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.15 | 5 / 230 |
| adipose | 2% | 3.46 | 26 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 3.59 | 17 / 929 | 0% | 0 | 0 / 0 |
| lung | 0% | 0.35 | 2 / 578 | 1% | 0.07 | 16 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 1% | 0.09 | 7 / 504 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.06 | 1 / 80 |
| heart | 0% | 0.65 | 4 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.73 | 6 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 0% | 5.04 | 1 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0050890 | Biological process | cognition |
| GO_0050775 | Biological process | positive regulation of dendrite morphogenesis |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_2000463 | Biological process | positive regulation of excitatory postsynaptic potential |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0061003 | Biological process | positive regulation of dendritic spine morphogenesis |
| GO_0007614 | Biological process | short-term memory |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| Gene name | CUX2 |
| Protein name | Neuron specific transcription factor Homeobox protein cut-like 2 (Homeobox protein cux-2) Transcription factor CUX2 Cut like homeobox 2 |
| Synonyms | KIAA0293 CUTL2 |
| Description | FUNCTION: Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III. Binds to DNA in a sequence-specific manner. . |
| Accessions | ENST00000261726.11 Q9BZX3 Q9BZV4 ENST00000397643.3 O14529 F5GWR6 |