CRYM | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	6 studies	32% ± 20%	Explore
respiratory goblet cell	5 studies	22% ± 5%	Explore
astrocyte	5 studies	41% ± 15%	Explore
Mueller cell	5 studies	43% ± 19%	Explore
club cell	4 studies	23% ± 4%	Explore
epithelial cell of proximal tubule	4 studies	18% ± 3%	Explore
brush cell	4 studies	46% ± 21%	Explore
cardiac muscle cell	4 studies	19% ± 3%	Explore
epithelial cell	3 studies	18% ± 1%	Explore
secretory cell	3 studies	21% ± 8%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	30% ± 14%	Explore
eye	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	89%	1933.71	79 / 89	85%	17.01	765 / 901
prostate	75%	1047.62	183 / 245	98%	52.64	494 / 502
brain	83%	5936.54	2190 / 2642	58%	16.78	411 / 705
liver	33%	200.01	74 / 226	80%	9.98	325 / 406
bladder	71%	699.76	15 / 21	36%	5.67	180 / 504
ureter	0%	0	0 / 0	100%	13.79	1 / 1
heart	95%	4054.26	821 / 861	0%	0	0 / 0
intestine	12%	81.73	118 / 966	59%	5.20	311 / 527
lung	14%	101.34	79 / 578	40%	12.50	465 / 1155
stomach	1%	5.82	2 / 359	42%	2.79	120 / 286
lymph node	0%	0	0 / 0	38%	18.97	11 / 29
esophagus	12%	85.96	167 / 1445	19%	0.94	34 / 183
uterus	2%	12.89	3 / 170	27%	8.30	124 / 459
skin	3%	17.62	50 / 1809	19%	2.15	92 / 472
pancreas	0%	0	0 / 328	20%	1.70	36 / 178
breast	1%	5.16	4 / 459	19%	3.09	209 / 1118
tonsil	0%	0	0 / 0	16%	3.62	7 / 45
muscle	9%	131.64	75 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	8%	1.57	6 / 80
adrenal gland	0%	5.02	1 / 258	6%	0.46	13 / 230
peripheral blood	6%	56.04	53 / 929	0%	0	0 / 0
ovary	0%	0	0 / 180	4%	0.45	16 / 430
adipose	3%	21.54	39 / 1204	0%	0	0 / 0
thymus	0%	0.64	1 / 653	2%	0.19	15 / 605
blood vessel	1%	10.95	14 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0006554	Biological process	lysine catabolic process
GO_0007605	Biological process	sensory perception of sound
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0042403	Biological process	thyroid hormone metabolic process
GO_0070327	Biological process	thyroid hormone transport
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005782	Cellular component	peroxisomal matrix
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0047127	Molecular function	thiomorpholine-carboxylate dehydrogenase activity
GO_0050661	Molecular function	NADP binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0070324	Molecular function	thyroid hormone binding

Gene name	CRYM
Protein name	Crystallin mu Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein)
Synonyms	THBP
Description	FUNCTION: Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. .
Accessions	Q14894 ENST00000543948.5 I3NI53 ENST00000572914.2 ENST00000572914 I3L3J9 ENST00000576703.5 I3L2W5 ENST00000570401.5 ENST00000574448.5 ENST00000571358.1 I3L325 ENST00000219599.8 I3L3Y1

CRYM report