Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 8 studies | 25% ± 7% | |
| epithelial cell | 5 studies | 28% ± 9% | |
| macrophage | 5 studies | 25% ± 7% | |
| glutamatergic neuron | 4 studies | 36% ± 17% | |
| ciliated cell | 4 studies | 25% ± 5% | |
| dendritic cell | 4 studies | 21% ± 4% | |
| astrocyte | 4 studies | 33% ± 7% | |
| oligodendrocyte | 4 studies | 25% ± 4% | |
| conventional dendritic cell | 3 studies | 27% ± 10% | |
| microglial cell | 3 studies | 23% ± 2% | |
| monocyte | 3 studies | 39% ± 30% | |
| abnormal cell | 3 studies | 23% ± 10% | |
| endothelial cell of lymphatic vessel | 3 studies | 19% ± 1% | |
| fibroblast | 3 studies | 18% ± 3% | |
| type II pneumocyte | 3 studies | 19% ± 4% | |
| goblet cell | 3 studies | 24% ± 9% | |
| transit amplifying cell | 3 studies | 33% ± 20% | |
| GABAergic neuron | 3 studies | 36% ± 15% | |
| interneuron | 3 studies | 42% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 1248.43 | 21 / 21 | 100% | 21.64 | 504 / 504 |
| breast | 100% | 1266.40 | 459 / 459 | 100% | 26.04 | 1118 / 1118 |
| esophagus | 100% | 1114.48 | 1445 / 1445 | 100% | 18.63 | 183 / 183 |
| intestine | 100% | 1257.20 | 966 / 966 | 100% | 20.75 | 527 / 527 |
| ovary | 100% | 1295.78 | 180 / 180 | 100% | 21.49 | 430 / 430 |
| prostate | 100% | 1213.81 | 245 / 245 | 100% | 19.67 | 502 / 502 |
| uterus | 100% | 1348.04 | 170 / 170 | 100% | 23.60 | 459 / 459 |
| thymus | 100% | 1268.29 | 653 / 653 | 100% | 19.14 | 604 / 605 |
| lung | 100% | 1184.84 | 577 / 578 | 100% | 16.67 | 1155 / 1155 |
| liver | 100% | 655.33 | 226 / 226 | 100% | 12.67 | 405 / 406 |
| stomach | 100% | 950.30 | 359 / 359 | 100% | 19.94 | 285 / 286 |
| brain | 99% | 754.30 | 2625 / 2642 | 100% | 16.93 | 705 / 705 |
| skin | 100% | 1484.00 | 1809 / 1809 | 99% | 19.95 | 468 / 472 |
| pancreas | 100% | 730.41 | 327 / 328 | 99% | 15.31 | 177 / 178 |
| kidney | 100% | 974.15 | 89 / 89 | 98% | 12.13 | 887 / 901 |
| adrenal gland | 100% | 1102.27 | 258 / 258 | 97% | 11.97 | 222 / 230 |
| adipose | 100% | 1152.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1183.79 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 32.06 | 29 / 29 |
| spleen | 100% | 1521.73 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 21.06 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.21 | 1 / 1 |
| muscle | 100% | 785.61 | 801 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1232.79 | 912 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 678.68 | 844 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 10.75 | 76 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006402 | Biological process | mRNA catabolic process |
| GO_0031047 | Biological process | regulatory ncRNA-mediated gene silencing |
| GO_0017148 | Biological process | negative regulation of translation |
| GO_0000289 | Biological process | nuclear-transcribed mRNA poly(A) tail shortening |
| GO_0030014 | Cellular component | CCR4-NOT complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CNOT10 |
| Protein name | CCR4-NOT transcription complex subunit 10 |
| Synonyms | |
| Description | FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. . FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. . FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. . FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. . FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. . |
| Accessions | ENST00000455381.5 ENST00000707745.1 [Q9H9A5-6] H7C0K1 ENST00000331889.10 [Q9H9A5-3] H7C1X9 E9PCN5 ENST00000707741.1 [Q9H9A5-1] ENST00000707740.1 [Q9H9A5-3] ENST00000328834.10 [Q9H9A5-1] Q9H9A5 ENST00000416457.5 H7BZZ7 ENST00000435630.5 ENST00000454516.7 [Q9H9A5-6] ENST00000430408.1 |