CNKSR3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070373Biological processnegative regulation of ERK1 and ERK2 cascade
GO_0033137Biological processnegative regulation of peptidyl-serine phosphorylation
GO_0010765Biological processpositive regulation of sodium ion transport
GO_0016324Cellular componentapical plasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCNKSR3
Protein nameCNKSR family member 3
Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein)
SynonymsMAGI1
DescriptionFUNCTION: Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC). .

AccessionsENST00000479339.5
A0A5H1ZRR2
ENST00000607772.6 [Q6P9H4-1]
ENST00000424998.3
Q6P9H4
Q5T4Y8