CNDP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0103046Molecular functionalanylglutamate dipeptidase activity
GO_0070573Molecular functionmetallodipeptidase activity
GO_0004180Molecular functioncarboxypeptidase activity
GO_0016805Molecular functiondipeptidase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCNDP2
Protein nameCarnosine dipeptidase 2
Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase)
Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Threonyl dipeptidase)
Alternative protein CNDP2
SynonymsHEL-S-13
CN2
CPGL
PEPA
DescriptionFUNCTION: Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue-specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism . Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis . Plays a role in the regulation of cell cycle arrest and apoptosis . .

AccessionsENST00000582589.5
ENST00000583216.5
J3QKQ0
ENST00000581513.5
ENST00000581912.1
J3KSV5
J3QL02
ENST00000579624.1
ENST00000584768.5
ENST00000579847.5 [Q96KP4-1]
J3QQN6
J3QR27
Q96KP4
J3KSS4
ENST00000583203.5
ENST00000584613.5
J3KRD5
J3QRD0
J3QRP4
J3KRJ8
J3QRH4
ENST00000583785.5
A0A087WYZ1
ENST00000577600.5
ENST00000324262.9 [Q96KP4-1]
L8EAZ5
J3QLU1
ENST00000581272.5
ENST00000579583.5
ENST00000580672.5
J3QKT2
ENST00000324301.12 [Q96KP4-2]
J3QRA8
A0A087WVS2
ENST00000582666.5
ENST00000582260.5
ENST00000577355.2