CLIC2 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	12 studies	24% ± 8%	Explore
endothelial cell of lymphatic vessel	11 studies	25% ± 10%	Explore
dendritic cell	10 studies	39% ± 14%	Explore
conventional dendritic cell	8 studies	24% ± 5%	Explore
endothelial cell of vascular tree	8 studies	25% ± 5%	Explore
vein endothelial cell	7 studies	25% ± 10%	Explore
macrophage	6 studies	26% ± 10%	Explore
type I pneumocyte	4 studies	23% ± 6%	Explore
capillary endothelial cell	4 studies	18% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLIC2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2897.46	653 / 653	100%	56.92	604 / 605
lung	100%	3074.55	578 / 578	92%	29.80	1063 / 1155
breast	100%	2048.55	459 / 459	92%	15.58	1023 / 1118
uterus	100%	1576.31	170 / 170	70%	16.26	321 / 459
kidney	91%	519.92	81 / 89	76%	16.97	685 / 901
esophagus	93%	846.99	1338 / 1445	73%	10.59	134 / 183
bladder	100%	1048.05	21 / 21	63%	9.38	315 / 504
adrenal gland	94%	501.73	243 / 258	64%	8.70	147 / 230
intestine	99%	1016.39	958 / 966	53%	6.29	280 / 527
prostate	91%	534.89	222 / 245	57%	4.82	285 / 502
ovary	99%	1378.22	179 / 180	44%	3.77	188 / 430
stomach	77%	500.16	275 / 359	64%	8.21	184 / 286
skin	78%	530.46	1415 / 1809	60%	13.04	285 / 472
brain	68%	294.03	1788 / 2642	62%	6.26	435 / 705
pancreas	24%	88.66	79 / 328	91%	16.37	162 / 178
adipose	100%	2417.07	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	32.48	29 / 29
spleen	100%	2904.20	241 / 241	0%	0	0 / 0
heart	97%	817.27	834 / 861	0%	0	0 / 0
blood vessel	94%	846.94	1259 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	20.61	37 / 45
liver	19%	71.32	43 / 226	42%	5.17	170 / 406
muscle	49%	204.05	390 / 803	0%	0	0 / 0
peripheral blood	45%	326.35	416 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	20%	3.80	16 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0060315	Biological process	negative regulation of ryanodine-sensitive calcium-release channel activity
GO_0098869	Biological process	cellular oxidant detoxification
GO_0006821	Biological process	chloride transport
GO_0007165	Biological process	signal transduction
GO_0051099	Biological process	positive regulation of binding
GO_0010881	Biological process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO_1902476	Biological process	chloride transmembrane transport
GO_0010880	Biological process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0034707	Cellular component	chloride channel complex
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004602	Molecular function	glutathione peroxidase activity
GO_0004364	Molecular function	glutathione transferase activity
GO_0005515	Molecular function	protein binding
GO_0005254	Molecular function	chloride channel activity

Gene name	CLIC2
Protein name	Chloride intracellular channel 2 isoform b Chloride intracellular channel 2 Chloride intracellular channel protein 2 (XAP121)
Synonyms	RP13-228J13.7-004
Description	FUNCTION: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. .
Accessions	O15247 ENST00000321926.4 Q86YM0 ENST00000369449.7 A6PVS0

CLIC2 report