CHRNA9 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNA9 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	86%	42.47	1553 / 1809	10%	0.98	47 / 472
brain	33%	3.08	867 / 2642	34%	4.44	237 / 705
thymus	50%	5.91	324 / 653	9%	0.23	52 / 605
spleen	44%	2.93	107 / 241	0%	0	0 / 0
lung	29%	3.05	170 / 578	14%	2.22	165 / 1155
bladder	33%	1.71	7 / 21	4%	0.79	22 / 504
uterus	5%	1.25	9 / 170	17%	1.48	77 / 459
peripheral blood	21%	1.41	192 / 929	0%	0	0 / 0
esophagus	10%	0.62	145 / 1445	9%	0.81	16 / 183
breast	7%	0.34	30 / 459	12%	8.35	130 / 1118
intestine	11%	0.75	109 / 966	1%	0.08	4 / 527
ovary	7%	0.37	13 / 180	4%	0.12	18 / 430
prostate	9%	0.45	22 / 245	0%	0	0 / 502
stomach	7%	0.37	24 / 359	1%	0.01	3 / 286
muscle	7%	0.54	58 / 803	0%	0	0 / 0
adrenal gland	5%	0.31	14 / 258	2%	0.41	4 / 230
pancreas	6%	0.57	19 / 328	1%	0.12	1 / 178
liver	5%	0.29	11 / 226	1%	0.02	6 / 406
kidney	6%	0.29	5 / 89	0%	0.03	4 / 901
blood vessel	5%	0.31	62 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.09	2 / 45
adipose	3%	0.17	39 / 1204	0%	0	0 / 0
heart	1%	0.10	11 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010996	Biological process	response to auditory stimulus
GO_0042391	Biological process	regulation of membrane potential
GO_0051899	Biological process	membrane depolarization
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0007268	Biological process	chemical synaptic transmission
GO_0042472	Biological process	inner ear morphogenesis
GO_0050910	Biological process	detection of mechanical stimulus involved in sensory perception of sound
GO_0070588	Biological process	calcium ion transmembrane transport
GO_0005886	Cellular component	plasma membrane
GO_1902495	Cellular component	transmembrane transporter complex
GO_0043005	Cellular component	neuron projection
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_0004888	Molecular function	transmembrane signaling receptor activity
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity
GO_0005515	Molecular function	protein binding
GO_0005262	Molecular function	calcium channel activity

Gene name	CHRNA9
Protein name	Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9)
Synonyms	NACHRA9
Description	FUNCTION: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane . The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane . In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion . .
Accessions	Q9UGM1 ENST00000310169.3

CHRNA9 report