Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 5 studies | 25% ± 4% | |
| glutamatergic neuron | 4 studies | 23% ± 10% | |
| GABAergic neuron | 3 studies | 26% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 187.73 | 2507 / 2642 | 13% | 0.39 | 93 / 705 |
| liver | 100% | 82.03 | 226 / 226 | 0% | 0.00 | 1 / 406 |
| spleen | 100% | 64.40 | 241 / 241 | 0% | 0 | 0 / 0 |
| lung | 97% | 37.82 | 561 / 578 | 3% | 0.05 | 32 / 1155 |
| thymus | 97% | 30.97 | 635 / 653 | 0% | 0.01 | 2 / 605 |
| uterus | 95% | 28.38 | 162 / 170 | 1% | 0.03 | 6 / 459 |
| blood vessel | 96% | 29.82 | 1279 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 95% | 31.96 | 232 / 245 | 1% | 0.01 | 4 / 502 |
| breast | 94% | 31.21 | 431 / 459 | 1% | 0.02 | 14 / 1118 |
| kidney | 94% | 24.92 | 84 / 89 | 1% | 0.02 | 6 / 901 |
| adipose | 91% | 24.20 | 1100 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 87% | 19.08 | 313 / 359 | 3% | 0.05 | 8 / 286 |
| intestine | 89% | 32.40 | 861 / 966 | 0% | 0.00 | 1 / 527 |
| pancreas | 85% | 19.06 | 280 / 328 | 1% | 0.02 | 2 / 178 |
| skin | 82% | 28.96 | 1483 / 1809 | 1% | 0.04 | 6 / 472 |
| bladder | 81% | 17.71 | 17 / 21 | 2% | 0.04 | 8 / 504 |
| ovary | 80% | 17.86 | 144 / 180 | 0% | 0.00 | 1 / 430 |
| esophagus | 76% | 14.39 | 1098 / 1445 | 2% | 0.04 | 4 / 183 |
| adrenal gland | 68% | 10.91 | 175 / 258 | 0% | 0.07 | 1 / 230 |
| heart | 67% | 11.67 | 577 / 861 | 0% | 0 | 0 / 0 |
| muscle | 66% | 12.49 | 533 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 13.42 | 591 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060304 | Biological process | regulation of phosphatidylinositol dephosphorylation |
| GO_0015872 | Biological process | dopamine transport |
| GO_0019226 | Biological process | transmission of nerve impulse |
| GO_0007197 | Biological process | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway |
| GO_0001696 | Biological process | gastric acid secretion |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0007213 | Biological process | G protein-coupled acetylcholine receptor signaling pathway |
| GO_0098664 | Biological process | G protein-coupled serotonin receptor signaling pathway |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045202 | Cellular component | synapse |
| GO_0004993 | Molecular function | G protein-coupled serotonin receptor activity |
| GO_0016907 | Molecular function | G protein-coupled acetylcholine receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004435 | Molecular function | phosphatidylinositol phospholipase C activity |
| Gene name | CHRM5 |
| Protein name | Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor M5 Cholinergic receptor muscarinic 5 |
| Synonyms | |
| Description | FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. . FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. . |
| Accessions | ENST00000560035.1 Q8IVW0 P08912 H0YKC0 ENST00000383263.7 Q6NUM3 ENST00000557872.1 |