CHAF1B | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHAF1B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	366.27	458 / 459	99%	15.57	1106 / 1118
skin	100%	581.70	1808 / 1809	99%	14.63	466 / 472
uterus	100%	418.16	170 / 170	98%	21.81	452 / 459
bladder	100%	217.33	21 / 21	94%	11.97	476 / 504
prostate	100%	381.69	245 / 245	94%	5.93	472 / 502
ovary	100%	288.96	180 / 180	93%	8.92	402 / 430
intestine	97%	240.34	936 / 966	96%	10.22	507 / 527
esophagus	96%	304.71	1393 / 1445	96%	10.57	176 / 183
lung	97%	238.58	558 / 578	93%	10.49	1072 / 1155
stomach	89%	195.35	320 / 359	95%	9.79	271 / 286
thymus	98%	207.47	642 / 653	82%	5.41	495 / 605
pancreas	100%	362.19	327 / 328	80%	4.63	142 / 178
brain	90%	358.94	2390 / 2642	49%	4.63	343 / 705
adrenal gland	83%	128.31	215 / 258	30%	1.73	69 / 230
kidney	73%	142.39	65 / 89	35%	1.89	311 / 901
lymph node	0%	0	0 / 0	100%	15.28	29 / 29
muscle	100%	1477.92	803 / 803	0%	0	0 / 0
spleen	100%	293.76	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	24.61	45 / 45
ureter	0%	0	0 / 0	100%	7.58	1 / 1
adipose	98%	265.49	1185 / 1204	0%	0	0 / 0
blood vessel	94%	172.83	1254 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	75%	4.29	60 / 80
peripheral blood	74%	454.53	689 / 929	0%	0	0 / 0
liver	31%	55.72	69 / 226	43%	3.76	174 / 406
heart	48%	64.39	411 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006335	Biological process	DNA replication-dependent chromatin assembly
GO_0006281	Biological process	DNA repair
GO_0006260	Biological process	DNA replication
GO_0006334	Biological process	nucleosome assembly
GO_0033186	Cellular component	CAF-1 complex
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000785	Cellular component	chromatin
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0051082	Molecular function	unfolded protein binding
GO_0005515	Molecular function	protein binding
GO_0042393	Molecular function	histone binding
GO_0003682	Molecular function	chromatin binding

Gene name	CHAF1B
Protein name	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)
Synonyms	MPP7 MPHOSPH7 CAF1P60 CAF1A
Description	FUNCTION: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. .
Accessions	Q13112 ENST00000314103.6

CHAF1B report