CAF-1 complex

I. Literature review

[source]
NameCAF-1 complex
IDGO_0033186
collection_id

Cellular component

Exact synonym

chromatin assembly factor 1 complex

Description

A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.

Comment

In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.

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Genes