CHAF1A | OmnibusX

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	11 studies	24% ± 8%	Explore
dendritic cell	3 studies	22% ± 5%	Explore
transit amplifying cell	3 studies	32% ± 8%	Explore
erythroblast	3 studies	28% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHAF1A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	1719.22	1809 / 1809	100%	30.17	472 / 472
uterus	100%	553.04	170 / 170	100%	44.21	458 / 459
esophagus	99%	848.40	1437 / 1445	100%	24.26	183 / 183
bladder	100%	694.05	21 / 21	99%	29.34	498 / 504
prostate	100%	856.04	245 / 245	99%	18.92	495 / 502
breast	100%	761.15	459 / 459	99%	20.63	1102 / 1118
intestine	100%	742.69	964 / 966	99%	25.55	520 / 527
stomach	99%	570.73	355 / 359	98%	23.20	281 / 286
ovary	99%	521.56	178 / 180	96%	13.35	411 / 430
lung	98%	645.38	567 / 578	95%	21.12	1101 / 1155
thymus	99%	456.79	644 / 653	94%	13.57	566 / 605
brain	99%	522.02	2606 / 2642	93%	15.51	659 / 705
pancreas	93%	323.26	306 / 328	93%	12.37	166 / 178
adrenal gland	98%	643.55	254 / 258	76%	8.75	175 / 230
liver	87%	288.96	196 / 226	81%	11.21	327 / 406
kidney	84%	323.56	75 / 89	77%	6.84	694 / 901
lymph node	0%	0	0 / 0	100%	46.99	29 / 29
muscle	100%	1027.22	803 / 803	0%	0	0 / 0
spleen	100%	1042.87	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	59.76	45 / 45
ureter	0%	0	0 / 0	100%	33.29	1 / 1
adipose	99%	638.80	1195 / 1204	0%	0	0 / 0
blood vessel	98%	426.02	1302 / 1335	0%	0	0 / 0
peripheral blood	92%	1181.92	855 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	88%	8.41	70 / 80
heart	87%	344.78	749 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006335	Biological process	DNA replication-dependent chromatin assembly
GO_0006281	Biological process	DNA repair
GO_0006260	Biological process	DNA replication
GO_0006334	Biological process	nucleosome assembly
GO_0033186	Cellular component	CAF-1 complex
GO_0032991	Cellular component	protein-containing complex
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0070087	Molecular function	chromo shadow domain binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0003682	Molecular function	chromatin binding
GO_0051082	Molecular function	unfolded protein binding

Gene name	CHAF1A
Protein name	Chromatin assembly factor 1 subunit A Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)
Synonyms	CAF1P150 CAF
Description	FUNCTION: Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. .
Accessions	K7EME9 K7EPA1 ENST00000589648.1 K7ENC7 Q13111 ENST00000585854.1 K7EJF1 ENST00000587739.1 ENST00000301280.10 [Q13111-1] ENST00000585371.1

CHAF1A report