Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 5 studies | 21% ± 3% | |
plasmablast | 5 studies | 33% ± 19% | |
ionocyte | 4 studies | 36% ± 7% | |
transit amplifying cell | 4 studies | 30% ± 5% | |
erythroblast | 4 studies | 38% ± 19% | |
basal cell | 4 studies | 26% ± 5% | |
epithelial cell | 4 studies | 37% ± 13% | |
erythrocyte | 4 studies | 33% ± 15% | |
CD4-positive, alpha-beta T cell | 4 studies | 27% ± 4% | |
CD8-positive, alpha-beta T cell | 4 studies | 23% ± 8% | |
deuterosomal cell | 3 studies | 21% ± 0% | |
hematopoietic precursor cell | 3 studies | 27% ± 10% | |
fibroblast | 3 studies | 17% ± 2% | |
connective tissue cell | 3 studies | 27% ± 14% | |
smooth muscle cell | 3 studies | 22% ± 5% | |
pro-B cell | 3 studies | 28% ± 7% | |
dendritic cell | 3 studies | 23% ± 6% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 99% | 447.48 | 169 / 170 | 99% | 219.16 | 456 / 459 |
intestine | 100% | 223.29 | 964 / 966 | 98% | 76.95 | 514 / 527 |
esophagus | 100% | 324.36 | 1445 / 1445 | 97% | 57.42 | 178 / 183 |
bladder | 100% | 142.05 | 21 / 21 | 94% | 77.30 | 476 / 504 |
skin | 99% | 349.23 | 1797 / 1809 | 88% | 33.36 | 416 / 472 |
ovary | 92% | 101.84 | 165 / 180 | 96% | 86.30 | 411 / 430 |
breast | 99% | 185.16 | 455 / 459 | 86% | 46.12 | 963 / 1118 |
stomach | 86% | 135.18 | 309 / 359 | 96% | 57.96 | 275 / 286 |
lung | 96% | 132.57 | 555 / 578 | 84% | 56.17 | 975 / 1155 |
prostate | 97% | 176.68 | 238 / 245 | 31% | 5.96 | 157 / 502 |
adrenal gland | 97% | 109.88 | 250 / 258 | 30% | 10.02 | 70 / 230 |
pancreas | 30% | 17.03 | 98 / 328 | 87% | 29.13 | 154 / 178 |
liver | 55% | 43.15 | 125 / 226 | 52% | 19.05 | 211 / 406 |
thymus | 89% | 70.37 | 581 / 653 | 17% | 14.57 | 101 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 80.03 | 29 / 29 |
tonsil | 0% | 0 | 0 / 0 | 100% | 207.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.28 | 1 / 1 |
spleen | 100% | 169.02 | 240 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 161.86 | 1184 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 94% | 105.93 | 1261 / 1335 | 0% | 0 | 0 / 0 |
kidney | 81% | 81.73 | 72 / 89 | 11% | 2.72 | 97 / 901 |
brain | 49% | 30.85 | 1296 / 2642 | 30% | 8.39 | 210 / 705 |
peripheral blood | 72% | 319.96 | 668 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 51% | 9.11 | 41 / 80 |
muscle | 48% | 35.13 | 388 / 803 | 0% | 0 | 0 / 0 |
heart | 20% | 12.07 | 176 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051301 | Biological process | cell division |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0051276 | Biological process | chromosome organization |
GO_0034080 | Biological process | CENP-A containing chromatin assembly |
GO_0007059 | Biological process | chromosome segregation |
GO_0051382 | Biological process | kinetochore assembly |
GO_0000775 | Cellular component | chromosome, centromeric region |
GO_0016363 | Cellular component | nuclear matrix |
GO_0005730 | Cellular component | nucleolus |
GO_0000776 | Cellular component | kinetochore |
GO_0005634 | Cellular component | nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000939 | Cellular component | inner kinetochore |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0003677 | Molecular function | DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CENPW |
Protein name | Centromere protein W Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein) |
Synonyms | C6orf173 CUG2 |
Description | FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis. . |
Accessions | Q5EE01 ENST00000368328.5 [Q5EE01-1] ENST00000368326.5 ENST00000368325.5 [Q5EE01-2] A0A0A0MRK5 |