Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 7 studies | 24% ± 5% | |
capillary endothelial cell | 4 studies | 17% ± 3% | |
non-classical monocyte | 4 studies | 19% ± 4% | |
endothelial cell | 4 studies | 24% ± 5% | |
endothelial cell of lymphatic vessel | 4 studies | 24% ± 7% | |
endothelial cell of vascular tree | 4 studies | 19% ± 0% | |
epithelial cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of CDC42EP2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 1288.51 | 965 / 966 | 0% | 0.00 | 2 / 527 |
kidney | 100% | 1037.93 | 89 / 89 | 0% | 0.00 | 1 / 901 |
adipose | 100% | 2948.54 | 1204 / 1204 | 0% | 0 | 0 / 0 |
bladder | 100% | 1757.10 | 21 / 21 | 0% | 0 | 0 / 504 |
breast | 100% | 2130.57 | 459 / 459 | 0% | 0 | 0 / 1118 |
ovary | 100% | 980.38 | 180 / 180 | 0% | 0 | 0 / 430 |
spleen | 100% | 1714.40 | 241 / 241 | 0% | 0 | 0 / 0 |
thymus | 100% | 1688.79 | 651 / 653 | 0% | 0 | 0 / 605 |
lung | 100% | 1824.90 | 576 / 578 | 0% | 0 | 0 / 1155 |
uterus | 99% | 1503.15 | 169 / 170 | 0% | 0 | 0 / 459 |
heart | 99% | 983.89 | 854 / 861 | 0% | 0 | 0 / 0 |
prostate | 99% | 1002.35 | 243 / 245 | 0% | 0 | 0 / 502 |
stomach | 97% | 1130.43 | 349 / 359 | 0% | 0.00 | 1 / 286 |
esophagus | 94% | 2053.47 | 1352 / 1445 | 1% | 0.01 | 1 / 183 |
skin | 89% | 1116.33 | 1616 / 1809 | 0% | 0 | 0 / 472 |
brain | 82% | 611.00 | 2165 / 2642 | 0% | 0 | 0 / 705 |
adrenal gland | 81% | 462.00 | 209 / 258 | 0% | 0 | 0 / 230 |
peripheral blood | 79% | 1249.99 | 734 / 929 | 0% | 0 | 0 / 0 |
muscle | 59% | 276.66 | 471 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 57% | 418.44 | 763 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 42% | 183.15 | 137 / 328 | 0% | 0 | 0 / 178 |
liver | 18% | 83.77 | 40 / 226 | 0% | 0 | 0 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0031334 | Biological process | positive regulation of protein-containing complex assembly |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0007015 | Biological process | actin filament organization |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0008360 | Biological process | regulation of cell shape |
GO_0031274 | Biological process | positive regulation of pseudopodium assembly |
GO_0071346 | Biological process | cellular response to type II interferon |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0012505 | Cellular component | endomembrane system |
GO_0016020 | Cellular component | membrane |
GO_0005829 | Cellular component | cytosol |
GO_0045335 | Cellular component | phagocytic vesicle |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0001515 | Molecular function | opioid peptide activity |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CDC42EP2 |
Protein name | Cdc42 effector protein 2 (Binder of Rho GTPases 1) |
Synonyms | BORG1 CEP2 |
Description | FUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. . |
Accessions | O14613 ENST00000533419.1 ENST00000279249.3 |