CDC42EP2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDC42EP2 at tissue level.

III. Associated gene sets

GO_0030838Biological processpositive regulation of actin filament polymerization
GO_0031334Biological processpositive regulation of protein-containing complex assembly
GO_0030036Biological processactin cytoskeleton organization
GO_0007015Biological processactin filament organization
GO_0007266Biological processRho protein signal transduction
GO_0008360Biological processregulation of cell shape
GO_0031274Biological processpositive regulation of pseudopodium assembly
GO_0071346Biological processcellular response to type II interferon
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0012505Cellular componentendomembrane system
GO_0016020Cellular componentmembrane
GO_0005829Cellular componentcytosol
GO_0045335Cellular componentphagocytic vesicle
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0001515Molecular functionopioid peptide activity
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDC42EP2
Protein nameCdc42 effector protein 2 (Binder of Rho GTPases 1)
SynonymsBORG1
CEP2
DescriptionFUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. .

AccessionsO14613
ENST00000533419.1
ENST00000279249.3