Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 43 studies | 69% ± 22% | |
classical monocyte | 27 studies | 65% ± 17% | |
conventional dendritic cell | 24 studies | 43% ± 16% | |
non-classical monocyte | 24 studies | 81% ± 15% | |
plasmacytoid dendritic cell | 21 studies | 59% ± 18% | |
monocyte | 20 studies | 59% ± 16% | |
dendritic cell | 14 studies | 43% ± 18% | |
myeloid cell | 11 studies | 69% ± 13% | |
platelet | 10 studies | 33% ± 11% | |
alveolar macrophage | 8 studies | 70% ± 28% | |
neutrophil | 8 studies | 49% ± 21% | |
mast cell | 7 studies | 20% ± 2% | |
mononuclear phagocyte | 6 studies | 56% ± 15% | |
enterocyte | 6 studies | 31% ± 7% | |
epithelial cell | 6 studies | 28% ± 11% | |
intermediate monocyte | 6 studies | 70% ± 24% | |
leukocyte | 5 studies | 45% ± 13% | |
adventitial cell | 4 studies | 16% ± 1% | |
inflammatory macrophage | 4 studies | 60% ± 23% | |
fibroblast | 4 studies | 16% ± 0% | |
tissue-resident macrophage | 3 studies | 68% ± 26% | |
microglial cell | 3 studies | 50% ± 17% | |
secretory cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3600.00 | 21 / 21 | 0% | 0 | 0 / 504 |
adipose | 100% | 9809.62 | 1201 / 1204 | 0% | 0 | 0 / 0 |
lung | 99% | 16548.02 | 575 / 578 | 0% | 0.00 | 3 / 1155 |
spleen | 99% | 18243.59 | 238 / 241 | 0% | 0 | 0 / 0 |
breast | 97% | 5404.93 | 447 / 459 | 0% | 0 | 0 / 1118 |
adrenal gland | 91% | 4889.89 | 234 / 258 | 0% | 0 | 0 / 230 |
blood vessel | 89% | 4817.69 | 1193 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 87% | 3248.89 | 1255 / 1445 | 2% | 0.03 | 3 / 183 |
peripheral blood | 88% | 14651.10 | 817 / 929 | 0% | 0 | 0 / 0 |
intestine | 86% | 4155.57 | 832 / 966 | 1% | 0.01 | 3 / 527 |
kidney | 82% | 3353.24 | 73 / 89 | 0% | 0.00 | 2 / 901 |
stomach | 72% | 2320.82 | 258 / 359 | 0% | 0.00 | 1 / 286 |
skin | 67% | 3290.42 | 1208 / 1809 | 0% | 0.01 | 2 / 472 |
thymus | 65% | 1733.81 | 427 / 653 | 0% | 0 | 0 / 605 |
liver | 62% | 2781.66 | 140 / 226 | 0% | 0 | 0 / 406 |
uterus | 55% | 1500.92 | 94 / 170 | 0% | 0 | 0 / 459 |
heart | 44% | 1285.38 | 383 / 861 | 0% | 0 | 0 / 0 |
prostate | 44% | 969.91 | 107 / 245 | 0% | 0 | 0 / 502 |
ovary | 37% | 842.16 | 66 / 180 | 0% | 0 | 0 / 430 |
muscle | 25% | 628.53 | 201 / 803 | 0% | 0 | 0 / 0 |
pancreas | 25% | 553.34 | 82 / 328 | 0% | 0 | 0 / 178 |
brain | 21% | 546.70 | 557 / 2642 | 0% | 0 | 0 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071222 | Biological process | cellular response to lipopolysaccharide |
GO_0002605 | Biological process | negative regulation of dendritic cell antigen processing and presentation |
GO_0031669 | Biological process | cellular response to nutrient levels |
GO_0140052 | Biological process | cellular response to oxidised low-density lipoprotein particle stimulus |
GO_0002437 | Biological process | inflammatory response to antigenic stimulus |
GO_0072594 | Biological process | establishment of protein localization to organelle |
GO_0005764 | Cellular component | lysosome |
GO_0035577 | Cellular component | azurophil granule membrane |
GO_0031902 | Cellular component | late endosome membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0016020 | Cellular component | membrane |
GO_0005515 | Molecular function | protein binding |
Gene name | CD68 |
Protein name | Macrosialin (Gp110) (CD antigen CD68) CD68 molecule |
Synonyms | |
Description | FUNCTION: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
Accessions | J3KT24 ENST00000250092.11 [P34810-1] J3KRX0 P34810 ENST00000584180.1 ENST00000380498.10 [P34810-3] ENST00000584502.1 |