Insufficient scRNA-seq data for expression of CCL16 at single-cell level.
Insufficient scRNA-seq data for expression of CCL16 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 3400.08 | 226 / 226 | 89% | 124.00 | 361 / 406 |
breast | 100% | 82.42 | 457 / 459 | 3% | 0.05 | 28 / 1118 |
spleen | 100% | 310.46 | 241 / 241 | 0% | 0 | 0 / 0 |
uterus | 99% | 119.34 | 168 / 170 | 1% | 0.01 | 3 / 459 |
prostate | 93% | 71.67 | 228 / 245 | 4% | 0.06 | 20 / 502 |
thymus | 94% | 61.30 | 615 / 653 | 1% | 0.01 | 4 / 605 |
adipose | 94% | 82.63 | 1136 / 1204 | 0% | 0 | 0 / 0 |
bladder | 90% | 45.43 | 19 / 21 | 2% | 0.02 | 8 / 504 |
kidney | 81% | 39.54 | 72 / 89 | 8% | 0.20 | 68 / 901 |
esophagus | 82% | 38.97 | 1179 / 1445 | 2% | 0.02 | 3 / 183 |
adrenal gland | 79% | 34.53 | 205 / 258 | 3% | 0.05 | 6 / 230 |
lung | 77% | 47.46 | 447 / 578 | 2% | 0.20 | 26 / 1155 |
intestine | 76% | 26.55 | 737 / 966 | 1% | 0.14 | 6 / 527 |
blood vessel | 64% | 27.18 | 857 / 1335 | 0% | 0 | 0 / 0 |
ovary | 49% | 20.37 | 88 / 180 | 0% | 0 | 0 / 430 |
skin | 45% | 13.53 | 818 / 1809 | 1% | 0.03 | 6 / 472 |
stomach | 42% | 13.93 | 151 / 359 | 3% | 0.10 | 9 / 286 |
heart | 36% | 11.44 | 312 / 861 | 0% | 0 | 0 / 0 |
muscle | 33% | 7.87 | 268 / 803 | 0% | 0 | 0 / 0 |
pancreas | 16% | 3.27 | 52 / 328 | 3% | 0.04 | 6 / 178 |
peripheral blood | 10% | 5.78 | 89 / 929 | 0% | 0 | 0 / 0 |
brain | 0% | 0.01 | 1 / 2642 | 0% | 0.00 | 1 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007154 | Biological process | cell communication |
GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
GO_0070098 | Biological process | chemokine-mediated signaling pathway |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0006954 | Biological process | inflammatory response |
GO_0006935 | Biological process | chemotaxis |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007267 | Biological process | cell-cell signaling |
GO_0048245 | Biological process | eosinophil chemotaxis |
GO_0050918 | Biological process | positive chemotaxis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0048020 | Molecular function | CCR chemokine receptor binding |
GO_0042056 | Molecular function | chemoattractant activity |
GO_0005515 | Molecular function | protein binding |
GO_0008009 | Molecular function | chemokine activity |
Gene name | CCL16 |
Protein name | C-C motif chemokine 16 (Chemokine CC-4) (HCC-4) (Chemokine LEC) (IL-10-inducible chemokine) (LCC-1) (Liver-expressed chemokine) (Lymphocyte and monocyte chemoattractant) (LMC) (Monotactin-1) (MTN-1) (NCC-4) (Small-inducible cytokine A16) C-C motif chemokine C-C motif chemokine 16 (C-C motif chemokine ligand 16) |
Synonyms | ILINCK NCC4 SCYA16 |
Description | FUNCTION: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. |
Accessions | ENST00000633277.1 ENST00000610493.1 A0A087WUU4 ENST00000611905.2 O15467 ENST00000631489.1 A0A087WUE5 ENST00000621559.2 ENST00000613642.4 |