CCKAR | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCKAR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	93%	710.30	333 / 359	12%	0.64	35 / 286
esophagus	44%	29.63	640 / 1445	4%	0.38	7 / 183
tonsil	0%	0	0 / 0	40%	1.27	18 / 45
breast	31%	9.71	141 / 459	4%	0.07	49 / 1118
brain	30%	10.33	790 / 2642	5%	0.16	34 / 705
intestine	28%	14.45	273 / 966	4%	0.24	22 / 527
kidney	26%	4.02	23 / 89	5%	0.77	48 / 901
pancreas	13%	2.88	41 / 328	6%	0.66	10 / 178
uterus	9%	2.09	16 / 170	5%	0.75	21 / 459
lung	2%	0.46	13 / 578	5%	0.36	60 / 1155
heart	7%	1.15	64 / 861	0%	0	0 / 0
adrenal gland	2%	0.26	5 / 258	3%	0.16	7 / 230
prostate	1%	0.09	2 / 245	3%	0.06	13 / 502
thymus	0%	0	0 / 653	3%	0.08	16 / 605
blood vessel	2%	0.35	28 / 1335	0%	0	0 / 0
bladder	0%	0	0 / 21	1%	0.04	7 / 504
skin	0%	0.06	7 / 1809	1%	0.16	4 / 472
ovary	0%	0	0 / 180	1%	0.24	4 / 430
liver	0%	0	0 / 226	0%	0.01	2 / 406
adipose	0%	0.45	2 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007409	Biological process	axonogenesis
GO_0046883	Biological process	regulation of hormone secretion
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0032870	Biological process	cellular response to hormone stimulus
GO_0001764	Biological process	neuron migration
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0038188	Biological process	cholecystokinin signaling pathway
GO_0030900	Biological process	forebrain development
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0042277	Molecular function	peptide binding
GO_0004951	Molecular function	cholecystokinin receptor activity
GO_0017046	Molecular function	peptide hormone binding

Gene name	CCKAR
Protein name	Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)
Synonyms	CCKRA
Description	FUNCTION: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Accessions	ENST00000295589.4 P32238

CCKAR report