CC2D1B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CC2D1B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CC2D1B at tissue level.

III. Associated gene sets

GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0010008Cellular componentendosome membrane
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005635Cellular componentnuclear envelope
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameCC2D1B
Protein nameCoiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)
Coiled-coil and C2 domain containing 1B
SynonymsLGD1
KIAA1836
DescriptionFUNCTION: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. .

AccessionsENST00000371586.6 [Q5T0F9-1]
ENST00000438021.5
ENST00000450942.2
H7C1U3
Q5T0F9
H0Y517
ENST00000284376.8 [Q5T0F9-2]