CAVIN3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901003Biological processnegative regulation of fermentation
GO_0051898Biological processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0070374Biological processpositive regulation of ERK1 and ERK2 cascade
GO_0030866Biological processcortical actin cytoskeleton organization
GO_0032922Biological processcircadian regulation of gene expression
GO_0032991Cellular componentprotein-containing complex
GO_0005829Cellular componentcytosol
GO_0005901Cellular componentcaveola
GO_0005737Cellular componentcytoplasm
GO_0005080Molecular functionprotein kinase C binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCAVIN3
Protein nameCaveolae-associated protein 3 (Cavin-3) (Protein kinase C delta-binding protein) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC)
Caveolae associated protein 3
SynonymsSRBC
PRKCDBP
DescriptionFUNCTION: Regulates the traffic and/or budding of caveolae . Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity). .

AccessionsENST00000303927.4
ENST00000530979.1
E9PIE3
Q969G5