CARD18 | OmnibusX

Name	Number of supported studies	Average coverage
Mueller cell	3 studies	23% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CARD18 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ureter	0%	0	0 / 0	100%	1.03	1 / 1
skin	71%	458.95	1281 / 1809	7%	0.61	31 / 472
esophagus	9%	9.94	134 / 1445	48%	3.46	87 / 183
lung	0%	1.57	1 / 578	22%	1.00	258 / 1155
liver	0%	0	0 / 226	18%	0.42	75 / 406
uterus	1%	0.48	1 / 170	15%	0.58	70 / 459
bladder	0%	0	0 / 21	15%	0.51	76 / 504
stomach	0%	1.01	1 / 359	13%	0.33	38 / 286
ovary	0%	0	0 / 180	13%	0.33	58 / 430
pancreas	0%	0.42	1 / 328	12%	0.29	21 / 178
intestine	0%	0.41	2 / 966	7%	0.21	39 / 527
tonsil	0%	0	0 / 0	7%	0.97	3 / 45
breast	0%	1.44	1 / 459	3%	0.30	32 / 1118
prostate	0%	0.58	1 / 245	2%	0.11	9 / 502
adrenal gland	0%	0	0 / 258	0%	0.04	1 / 230
heart	0%	0.59	3 / 861	0%	0	0 / 0
adipose	0%	1.02	3 / 1204	0%	0	0 / 0
blood vessel	0%	1.04	3 / 1335	0%	0	0 / 0
kidney	0%	0	0 / 89	0%	0.01	2 / 901
thymus	0%	0.40	1 / 653	0%	0	0 / 605
brain	0%	0	0 / 2642	0%	0.00	1 / 705
muscle	0%	0.11	1 / 803	0%	0	0 / 0
peripheral blood	0%	1.83	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0097340	Biological process	inhibition of cysteine-type endopeptidase activity
GO_0042981	Biological process	regulation of apoptotic process
GO_0032091	Biological process	negative regulation of protein binding
GO_0006954	Biological process	inflammatory response
GO_0032691	Biological process	negative regulation of interleukin-1 beta production
GO_0032991	Cellular component	protein-containing complex
GO_0050700	Molecular function	CARD domain binding
GO_0004869	Molecular function	cysteine-type endopeptidase inhibitor activity
GO_0089720	Molecular function	caspase binding
GO_0005515	Molecular function	protein binding

Gene name	CARD18
Protein name	Caspase recruitment domain family member 18 (ICEBERG caspase-1 inhibitor) Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg)
Synonyms	UNQ5804/PRO19611 ICEBERG hCG_1645817
Description	FUNCTION: Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. .
Accessions	ENST00000526823.1 G5EA35 P57730 ENST00000530950.2 ENST00000532895.1 ENST00000649856.1

CARD18 report