Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 13 studies | 70% ± 25% | |
GABAergic neuron | 10 studies | 67% ± 24% | |
neuron | 6 studies | 39% ± 17% | |
interneuron | 6 studies | 68% ± 23% | |
retinal ganglion cell | 5 studies | 69% ± 19% | |
astrocyte | 5 studies | 34% ± 17% | |
granule cell | 4 studies | 55% ± 20% | |
amacrine cell | 4 studies | 48% ± 25% | |
endothelial cell | 3 studies | 53% ± 24% | |
GABAergic interneuron | 3 studies | 77% ± 4% | |
GABAergic amacrine cell | 3 studies | 42% ± 14% | |
glycinergic amacrine cell | 3 studies | 21% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 14 studies | 48% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 97% | 4910.86 | 2566 / 2642 | 68% | 4.33 | 477 / 705 |
adrenal gland | 17% | 209.22 | 45 / 258 | 73% | 15.42 | 167 / 230 |
ovary | 0% | 0 | 0 / 180 | 69% | 3.48 | 296 / 430 |
tonsil | 0% | 0 | 0 / 0 | 56% | 2.11 | 25 / 45 |
prostate | 13% | 69.83 | 33 / 245 | 22% | 0.61 | 109 / 502 |
lung | 0% | 0 | 0 / 578 | 34% | 2.13 | 391 / 1155 |
esophagus | 0% | 0.56 | 2 / 1445 | 32% | 1.36 | 58 / 183 |
uterus | 4% | 32.64 | 6 / 170 | 26% | 1.04 | 121 / 459 |
eye | 0% | 0 | 0 / 0 | 24% | 0.42 | 19 / 80 |
thymus | 8% | 40.79 | 52 / 653 | 13% | 0.99 | 77 / 605 |
intestine | 13% | 58.36 | 121 / 966 | 6% | 0.23 | 34 / 527 |
stomach | 8% | 35.53 | 28 / 359 | 7% | 0.29 | 20 / 286 |
pancreas | 1% | 2.64 | 2 / 328 | 13% | 1.16 | 23 / 178 |
bladder | 0% | 0 | 0 / 21 | 9% | 0.47 | 46 / 504 |
breast | 0% | 0 | 0 / 459 | 9% | 0.31 | 99 / 1118 |
skin | 0% | 0.63 | 2 / 1809 | 8% | 0.27 | 39 / 472 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
kidney | 0% | 0 | 0 / 89 | 2% | 0.12 | 15 / 901 |
liver | 0% | 0 | 0 / 226 | 1% | 0.04 | 5 / 406 |
adipose | 1% | 5.67 | 9 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 3.34 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0098703 | Biological process | calcium ion import across plasma membrane |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_1904645 | Biological process | response to amyloid-beta |
GO_0005891 | Cellular component | voltage-gated calcium channel complex |
GO_0045202 | Cellular component | synapse |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005886 | Cellular component | plasma membrane |
GO_0008331 | Molecular function | high voltage-gated calcium channel activity |
GO_0005245 | Molecular function | voltage-gated calcium channel activity |
GO_0001540 | Molecular function | amyloid-beta binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | CACNA1B |
Protein name | Voltage-dependent N-type calcium channel subunit alpha Calcium channel alpha12.2 subunit Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III) (BIII) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Voltage-gated calcium channel subunit alpha Cav2.2) Calcium voltage-gated channel subunit alpha1 B |
Synonyms | CACH5 CACNL1A5 |
Description | FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals (By similarity). . FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. . FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. . |
Accessions | Q9HBG2 ENST00000371363.5 H0Y7I8 B1AQK7 Q9HAT4 Q9HBG3 Q9HAT6 ENST00000371357.5 Q9HBI3 Q9HAT5 Q9HBH4 ENST00000371372.6 [Q00975-1] Q9HBG1 Q9HBH3 B1AQK6 Q9HAT3 ENST00000277551.6 [Q00975-2] Q9HBH2 Q9HBI4 Q00975 ENST00000413253.1 |