Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 13 studies | 49% ± 21% | |
oligodendrocyte precursor cell | 11 studies | 36% ± 15% | |
adipocyte | 9 studies | 30% ± 10% | |
microglial cell | 7 studies | 20% ± 6% | |
macrophage | 7 studies | 29% ± 9% | |
endothelial cell of lymphatic vessel | 5 studies | 24% ± 2% | |
type II pneumocyte | 5 studies | 25% ± 10% | |
endothelial cell | 4 studies | 33% ± 12% | |
GABAergic neuron | 4 studies | 26% ± 10% | |
fibroblast | 4 studies | 20% ± 6% | |
glutamatergic neuron | 3 studies | 34% ± 17% | |
type I pneumocyte | 3 studies | 23% ± 4% | |
melanocyte | 3 studies | 48% ± 24% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 25% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2193.05 | 459 / 459 | 98% | 20.67 | 1095 / 1118 |
kidney | 100% | 1879.30 | 89 / 89 | 90% | 16.02 | 814 / 901 |
thymus | 99% | 1776.38 | 649 / 653 | 88% | 10.47 | 535 / 605 |
skin | 91% | 1597.28 | 1638 / 1809 | 95% | 90.10 | 447 / 472 |
brain | 96% | 5170.61 | 2528 / 2642 | 84% | 15.24 | 589 / 705 |
stomach | 88% | 973.63 | 316 / 359 | 85% | 11.44 | 243 / 286 |
lung | 97% | 1582.73 | 561 / 578 | 72% | 10.16 | 832 / 1155 |
uterus | 94% | 1035.99 | 159 / 170 | 59% | 8.20 | 273 / 459 |
liver | 86% | 717.38 | 194 / 226 | 67% | 5.94 | 272 / 406 |
ovary | 52% | 331.29 | 93 / 180 | 96% | 18.40 | 411 / 430 |
intestine | 51% | 338.57 | 496 / 966 | 80% | 8.51 | 422 / 527 |
esophagus | 62% | 525.11 | 892 / 1445 | 68% | 12.05 | 125 / 183 |
bladder | 71% | 639.10 | 15 / 21 | 52% | 4.92 | 260 / 504 |
prostate | 70% | 557.13 | 172 / 245 | 41% | 2.30 | 205 / 502 |
adrenal gland | 47% | 294.13 | 121 / 258 | 59% | 5.65 | 136 / 230 |
eye | 0% | 0 | 0 / 0 | 100% | 275.27 | 80 / 80 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.67 | 1 / 1 |
adipose | 99% | 2532.15 | 1197 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 12% | 64.84 | 39 / 328 | 85% | 9.05 | 152 / 178 |
blood vessel | 81% | 1074.06 | 1076 / 1335 | 0% | 0 | 0 / 0 |
spleen | 64% | 538.85 | 154 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 7.80 | 10 / 29 |
tonsil | 0% | 0 | 0 / 0 | 31% | 2.15 | 14 / 45 |
heart | 30% | 216.58 | 262 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 900.14 | 175 / 929 | 0% | 0 | 0 / 0 |
muscle | 2% | 12.11 | 18 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051301 | Biological process | cell division |
GO_0007399 | Biological process | nervous system development |
GO_0051726 | Biological process | regulation of cell cycle |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
Gene name | CABLES1 |
Protein name | Cdk5 and Abl enzyme substrate 1 CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1) |
Synonyms | CABLES |
Description | FUNCTION: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity). . |
Accessions | A0A0G2JLG8 ENST00000420687.2 [Q8TDN4-2] ENST00000579963.5 ENST00000582882.5 ENST00000580153.5 ENST00000400473.6 [Q8TDN4-4] J3QRY5 Q8TDN4 V9GYB4 ENST00000256925.12 [Q8TDN4-1] |