Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 14 studies | 27% ± 13% | |
| glutamatergic neuron | 12 studies | 53% ± 26% | |
| oligodendrocyte precursor cell | 11 studies | 36% ± 15% | |
| GABAergic neuron | 10 studies | 51% ± 25% | |
| microglial cell | 10 studies | 31% ± 8% | |
| oligodendrocyte | 10 studies | 27% ± 9% | |
| macrophage | 9 studies | 38% ± 11% | |
| astrocyte | 8 studies | 30% ± 13% | |
| neuron | 6 studies | 34% ± 14% | |
| epithelial cell | 6 studies | 25% ± 12% | |
| interneuron | 5 studies | 62% ± 22% | |
| ciliated cell | 5 studies | 25% ± 9% | |
| retinal cone cell | 5 studies | 27% ± 12% | |
| monocyte | 5 studies | 23% ± 8% | |
| fibroblast | 5 studies | 22% ± 4% | |
| granule cell | 4 studies | 41% ± 8% | |
| retinal ganglion cell | 4 studies | 42% ± 26% | |
| cardiac muscle cell | 4 studies | 16% ± 1% | |
| retinal rod cell | 4 studies | 33% ± 8% | |
| endothelial cell of lymphatic vessel | 4 studies | 22% ± 3% | |
| smooth muscle cell | 4 studies | 20% ± 3% | |
| goblet cell | 4 studies | 28% ± 18% | |
| progenitor cell | 3 studies | 27% ± 1% | |
| dendritic cell | 3 studies | 18% ± 2% | |
| amacrine cell | 3 studies | 33% ± 12% | |
| myeloid cell | 3 studies | 30% ± 8% | |
| alveolar macrophage | 3 studies | 30% ± 8% | |
| lymphocyte | 3 studies | 23% ± 8% | |
| pericyte | 3 studies | 21% ± 6% | |
| transit amplifying cell | 3 studies | 33% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2569.15 | 1445 / 1445 | 100% | 28.21 | 183 / 183 |
| breast | 100% | 2849.64 | 459 / 459 | 100% | 29.12 | 1116 / 1118 |
| prostate | 100% | 2668.17 | 245 / 245 | 100% | 20.40 | 501 / 502 |
| ovary | 100% | 3682.68 | 180 / 180 | 100% | 20.65 | 429 / 430 |
| lung | 100% | 2610.56 | 577 / 578 | 100% | 22.21 | 1153 / 1155 |
| uterus | 100% | 3959.43 | 170 / 170 | 100% | 22.73 | 457 / 459 |
| thymus | 100% | 3866.94 | 653 / 653 | 100% | 28.04 | 602 / 605 |
| brain | 99% | 4075.70 | 2628 / 2642 | 100% | 26.30 | 705 / 705 |
| kidney | 100% | 2606.31 | 89 / 89 | 99% | 22.10 | 896 / 901 |
| bladder | 100% | 2757.57 | 21 / 21 | 99% | 19.25 | 501 / 504 |
| intestine | 100% | 3546.13 | 966 / 966 | 99% | 25.29 | 523 / 527 |
| stomach | 100% | 2718.33 | 359 / 359 | 99% | 24.79 | 282 / 286 |
| pancreas | 99% | 1644.50 | 326 / 328 | 99% | 23.47 | 176 / 178 |
| adrenal gland | 100% | 2317.90 | 258 / 258 | 98% | 21.40 | 226 / 230 |
| skin | 100% | 2424.79 | 1805 / 1809 | 94% | 17.02 | 446 / 472 |
| liver | 100% | 1054.92 | 226 / 226 | 82% | 9.11 | 332 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 18.32 | 29 / 29 |
| spleen | 100% | 3547.35 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 23.98 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.23 | 1 / 1 |
| adipose | 100% | 2738.30 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2735.45 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 97% | 1204.80 | 776 / 803 | 0% | 0 | 0 / 0 |
| heart | 96% | 1436.49 | 826 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 12.90 | 71 / 80 |
| peripheral blood | 69% | 1397.83 | 643 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0065002 | Biological process | intracellular protein transmembrane transport |
| GO_0008286 | Biological process | insulin receptor signaling pathway |
| GO_0031340 | Biological process | positive regulation of vesicle fusion |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0090314 | Biological process | positive regulation of protein targeting to membrane |
| GO_0010828 | Biological process | positive regulation of glucose transmembrane transport |
| GO_0032587 | Cellular component | ruffle membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005938 | Cellular component | cell cortex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0034451 | Cellular component | centriolar satellite |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005544 | Molecular function | calcium-dependent phospholipid binding |
| Gene name | C2CD5 |
| Protein name | C2 calcium dependent domain containing 5 C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa) |
| Synonyms | KIAA0528 CDP138 |
| Description | FUNCTION: Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM. . |
| Accessions | ENST00000396028.6 [Q86YS7-2] ENST00000535555.1 ENST00000542683.1 H0YFC4 ENST00000545552.5 [Q86YS7-5] ENST00000536386.5 [Q86YS7-4] ENST00000539615.1 H0YGU7 ENST00000542676.5 [Q86YS7-3] ENST00000333957.8 [Q86YS7-1] ENST00000446597.6 [Q86YS7-3] H0YFE9 Q86YS7 |