BIRC8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of BIRC8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BIRC8 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0031398Biological processpositive regulation of protein ubiquitination
GO_0043066Biological processnegative regulation of apoptotic process
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0051726Biological processregulation of cell cycle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0043027Molecular functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameBIRC8
Protein nameBaculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Baculoviral IAP repeat-containing 8
SynonymsILP2
DescriptionFUNCTION: Protects against apoptosis mediated by BAX.

AccessionsQ6PIA0
Q96P09