Insufficient scRNA-seq data for expression of BHLHA15 at single-cell level.
Insufficient scRNA-seq data for expression of BHLHA15 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 92% | 230.75 | 226 / 245 | 99% | 64.40 | 499 / 502 |
pancreas | 100% | 6194.38 | 328 / 328 | 62% | 12.24 | 110 / 178 |
liver | 81% | 103.05 | 182 / 226 | 71% | 6.13 | 287 / 406 |
stomach | 77% | 742.00 | 277 / 359 | 69% | 5.34 | 198 / 286 |
lung | 62% | 22.58 | 359 / 578 | 81% | 8.88 | 937 / 1155 |
intestine | 47% | 34.42 | 456 / 966 | 69% | 4.90 | 366 / 527 |
spleen | 96% | 171.58 | 231 / 241 | 0% | 0 | 0 / 0 |
breast | 31% | 12.49 | 141 / 459 | 61% | 4.82 | 684 / 1118 |
kidney | 35% | 10.31 | 31 / 89 | 41% | 2.45 | 365 / 901 |
tonsil | 0% | 0 | 0 / 0 | 73% | 7.50 | 33 / 45 |
esophagus | 29% | 11.38 | 413 / 1445 | 43% | 2.74 | 79 / 183 |
skin | 37% | 11.88 | 665 / 1809 | 34% | 2.36 | 162 / 472 |
thymus | 47% | 16.70 | 309 / 653 | 22% | 1.36 | 135 / 605 |
ovary | 2% | 0.24 | 3 / 180 | 57% | 3.06 | 244 / 430 |
brain | 46% | 12.40 | 1216 / 2642 | 12% | 0.37 | 84 / 705 |
bladder | 14% | 4.10 | 3 / 21 | 40% | 2.69 | 203 / 504 |
uterus | 5% | 0.72 | 8 / 170 | 40% | 2.74 | 185 / 459 |
peripheral blood | 41% | 48.86 | 383 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 2.46 | 10 / 29 |
adrenal gland | 14% | 3.62 | 36 / 258 | 1% | 0.05 | 3 / 230 |
muscle | 13% | 2.92 | 105 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 0.33 | 5 / 80 |
blood vessel | 5% | 2.37 | 68 / 1335 | 0% | 0 | 0 / 0 |
adipose | 5% | 3.70 | 59 / 1204 | 0% | 0 | 0 / 0 |
heart | 3% | 0.79 | 29 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042149 | Biological process | cellular response to glucose starvation |
GO_0061564 | Biological process | axon development |
GO_0019722 | Biological process | calcium-mediated signaling |
GO_0048312 | Biological process | intracellular distribution of mitochondria |
GO_0048663 | Biological process | neuron fate commitment |
GO_0051674 | Biological process | localization of cell |
GO_0044331 | Biological process | cell-cell adhesion mediated by cadherin |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0007267 | Biological process | cell-cell signaling |
GO_0045216 | Biological process | cell-cell junction organization |
GO_0072560 | Biological process | type B pancreatic cell maturation |
GO_0030968 | Biological process | endoplasmic reticulum unfolded protein response |
GO_0010832 | Biological process | negative regulation of myotube differentiation |
GO_0007030 | Biological process | Golgi organization |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0006851 | Biological process | mitochondrial calcium ion transmembrane transport |
GO_0007423 | Biological process | sensory organ development |
GO_0042593 | Biological process | glucose homeostasis |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0070888 | Molecular function | E-box binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | BHLHA15 |
Protein name | Class A basic helix-loop-helix protein 15 (bHLHa15) (Class B basic helix-loop-helix protein 8) (bHLHb8) (Muscle, intestine and stomach expression 1) (MIST-1) |
Synonyms | BHLHB8 MIST1 |
Description | FUNCTION: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). . |
Accessions | ENST00000314018.2 Q7RTS1 ENST00000609256.2 |