BBOF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007288Biological processsperm axoneme assembly
GO_0030317Biological processflagellated sperm motility
GO_0044458Biological processmotile cilium assembly
GO_0005930Cellular componentaxoneme
GO_0036064Cellular componentciliary basal body
GO_0036126Cellular componentsperm flagellum

IV. Literature review

[source]
Gene nameBBOF1
Protein nameBasal body-orientation factor 1 (Coiled-coil domain-containing protein 176)
SynonymsCCDC176
C14orf45
DescriptionFUNCTION: Plays an essential role in sperm motility and male fertility by stabilizing the sperm flagellar axonemal structure. May be required for the stability of ODF2 and MANS1 proteins. Dispensable for the assembly and function of motile cilia. .

AccessionsA0A0B4J2D7
ENST00000394009.5
ENST00000464394.5
G3V488
Q8ND07
ENST00000463558.3