Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 29% ± 10% | |
mast cell | 17 studies | 27% ± 10% | |
astrocyte | 12 studies | 29% ± 12% | |
club cell | 10 studies | 32% ± 15% | |
GABAergic neuron | 9 studies | 32% ± 20% | |
ciliated cell | 9 studies | 27% ± 8% | |
monocyte | 8 studies | 23% ± 4% | |
respiratory goblet cell | 8 studies | 38% ± 14% | |
glutamatergic neuron | 8 studies | 37% ± 23% | |
fibroblast | 8 studies | 22% ± 9% | |
endothelial cell of lymphatic vessel | 7 studies | 22% ± 6% | |
classical monocyte | 7 studies | 24% ± 8% | |
epithelial cell | 7 studies | 41% ± 22% | |
macrophage | 7 studies | 20% ± 3% | |
secretory cell | 6 studies | 25% ± 10% | |
neuron | 6 studies | 31% ± 13% | |
basal cell | 6 studies | 30% ± 7% | |
adipocyte | 6 studies | 23% ± 3% | |
vein endothelial cell | 6 studies | 23% ± 4% | |
type II pneumocyte | 6 studies | 27% ± 5% | |
non-classical monocyte | 5 studies | 25% ± 10% | |
interneuron | 5 studies | 37% ± 21% | |
microglial cell | 5 studies | 20% ± 4% | |
myeloid cell | 5 studies | 30% ± 14% | |
squamous epithelial cell | 4 studies | 45% ± 21% | |
capillary endothelial cell | 4 studies | 20% ± 3% | |
endothelial cell of artery | 4 studies | 17% ± 2% | |
endothelial cell of vascular tree | 4 studies | 20% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 8% | |
smooth muscle cell | 4 studies | 17% ± 1% | |
oligodendrocyte | 4 studies | 25% ± 6% | |
GABAergic interneuron | 3 studies | 23% ± 5% | |
granule cell | 3 studies | 19% ± 3% | |
retinal ganglion cell | 3 studies | 34% ± 10% | |
brush cell | 3 studies | 30% ± 9% | |
mesothelial cell | 3 studies | 22% ± 1% | |
lymphocyte | 3 studies | 20% ± 2% | |
cholangiocyte | 3 studies | 42% ± 20% | |
type I pneumocyte | 3 studies | 21% ± 2% | |
abnormal cell | 3 studies | 27% ± 12% | |
alveolar macrophage | 3 studies | 34% ± 12% | |
natural killer cell | 3 studies | 17% ± 1% | |
goblet cell | 3 studies | 32% ± 17% | |
mucus secreting cell | 3 studies | 26% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 4421.43 | 180 / 180 | 100% | 124.57 | 430 / 430 |
intestine | 100% | 4654.99 | 966 / 966 | 100% | 96.34 | 526 / 527 |
lung | 100% | 6551.83 | 578 / 578 | 100% | 97.81 | 1151 / 1155 |
esophagus | 100% | 5935.52 | 1444 / 1445 | 99% | 114.68 | 182 / 183 |
kidney | 100% | 4071.78 | 89 / 89 | 98% | 130.52 | 883 / 901 |
bladder | 100% | 5200.33 | 21 / 21 | 98% | 85.65 | 492 / 504 |
stomach | 98% | 3124.85 | 351 / 359 | 100% | 105.28 | 285 / 286 |
uterus | 100% | 4680.75 | 170 / 170 | 97% | 93.37 | 447 / 459 |
breast | 100% | 4632.44 | 459 / 459 | 97% | 69.12 | 1083 / 1118 |
skin | 96% | 2706.61 | 1738 / 1809 | 99% | 118.14 | 466 / 472 |
brain | 95% | 2925.95 | 2512 / 2642 | 100% | 94.36 | 703 / 705 |
prostate | 100% | 3534.38 | 244 / 245 | 94% | 40.85 | 472 / 502 |
thymus | 100% | 2995.36 | 650 / 653 | 89% | 46.27 | 541 / 605 |
pancreas | 78% | 1370.54 | 256 / 328 | 98% | 101.56 | 175 / 178 |
adrenal gland | 100% | 10925.55 | 258 / 258 | 70% | 48.28 | 162 / 230 |
liver | 95% | 2463.63 | 215 / 226 | 68% | 33.22 | 275 / 406 |
adipose | 100% | 5485.32 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 9140.91 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4903.37 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 35.65 | 1 / 1 |
blood vessel | 100% | 3431.57 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 8717.26 | 922 / 929 | 0% | 0 | 0 / 0 |
heart | 96% | 2759.62 | 830 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 72.82 | 43 / 45 |
eye | 0% | 0 | 0 / 0 | 78% | 26.62 | 62 / 80 |
lymph node | 0% | 0 | 0 / 0 | 72% | 35.61 | 21 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010706 | Biological process | ganglioside biosynthetic process via lactosylceramide |
GO_0016266 | Biological process | O-glycan processing |
GO_0021955 | Biological process | central nervous system neuron axonogenesis |
GO_0005975 | Biological process | carbohydrate metabolic process |
GO_0022010 | Biological process | central nervous system myelination |
GO_0009101 | Biological process | glycoprotein biosynthetic process |
GO_0070085 | Biological process | glycosylation |
GO_0040019 | Biological process | positive regulation of embryonic development |
GO_0042551 | Biological process | neuron maturation |
GO_0030311 | Biological process | poly-N-acetyllactosamine biosynthetic process |
GO_0031647 | Biological process | regulation of protein stability |
GO_0006486 | Biological process | protein glycosylation |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0000139 | Cellular component | Golgi membrane |
GO_0032580 | Cellular component | Golgi cisterna membrane |
GO_0003945 | Molecular function | N-acetyllactosamine synthase activity |
GO_0008378 | Molecular function | galactosyltransferase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0008489 | Molecular function | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity |
Gene name | B4GALT5 |
Protein name | Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (EC 2.4.1.-) (Beta-1,4-GalT II) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5) |
Synonyms | |
Description | FUNCTION: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity). . |
Accessions | ENST00000371711.4 O43286 |