Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 22% ± 4% | |
| epithelial cell | 5 studies | 31% ± 10% | |
| fibroblast | 4 studies | 21% ± 3% | |
| type I pneumocyte | 4 studies | 18% ± 3% | |
| astrocyte | 4 studies | 24% ± 5% | |
| glutamatergic neuron | 4 studies | 41% ± 15% | |
| ciliated cell | 3 studies | 22% ± 3% | |
| lymphocyte | 3 studies | 16% ± 0% | |
| GABAergic neuron | 3 studies | 43% ± 6% | |
| dendritic cell | 3 studies | 20% ± 3% | |
| basal cell | 3 studies | 30% ± 8% | |
| transit amplifying cell | 3 studies | 24% ± 13% | |
| neuron | 3 studies | 21% ± 6% | |
| oligodendrocyte | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 855.81 | 1445 / 1445 | 100% | 32.07 | 183 / 183 |
| intestine | 100% | 1042.27 | 966 / 966 | 100% | 28.86 | 527 / 527 |
| lung | 100% | 1052.38 | 578 / 578 | 100% | 31.89 | 1155 / 1155 |
| ovary | 100% | 1297.97 | 180 / 180 | 100% | 38.10 | 430 / 430 |
| stomach | 100% | 732.45 | 359 / 359 | 100% | 29.44 | 285 / 286 |
| breast | 100% | 1229.44 | 459 / 459 | 100% | 28.50 | 1114 / 1118 |
| bladder | 100% | 983.00 | 21 / 21 | 99% | 24.29 | 501 / 504 |
| uterus | 100% | 1174.74 | 170 / 170 | 99% | 29.95 | 456 / 459 |
| thymus | 100% | 1324.38 | 653 / 653 | 99% | 35.81 | 598 / 605 |
| prostate | 100% | 980.46 | 245 / 245 | 99% | 25.89 | 495 / 502 |
| kidney | 100% | 827.24 | 89 / 89 | 97% | 21.20 | 875 / 901 |
| adrenal gland | 100% | 1374.43 | 258 / 258 | 97% | 20.33 | 222 / 230 |
| brain | 96% | 494.82 | 2546 / 2642 | 99% | 14.91 | 701 / 705 |
| pancreas | 98% | 466.85 | 320 / 328 | 98% | 21.30 | 174 / 178 |
| liver | 100% | 606.52 | 226 / 226 | 93% | 14.28 | 378 / 406 |
| skin | 100% | 1160.78 | 1807 / 1809 | 92% | 20.07 | 434 / 472 |
| adipose | 100% | 1263.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1121.81 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.77 | 29 / 29 |
| muscle | 100% | 1527.20 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 973.35 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.50 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.41 | 1 / 1 |
| heart | 98% | 603.13 | 844 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 89% | 722.12 | 823 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 68% | 7.42 | 54 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0010976 | Biological process | positive regulation of neuron projection development |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0019933 | Biological process | cAMP-mediated signaling |
| GO_0014074 | Biological process | response to purine-containing compound |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0045740 | Biological process | positive regulation of DNA replication |
| GO_0032025 | Biological process | response to cobalt ion |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_1990589 | Cellular component | ATF4-CREB1 transcription factor complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_1990590 | Cellular component | ATF1-ATF4 transcription factor complex |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ATF1 |
| Protein name | Activating transcription factor 1 Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (Protein TREB36) |
| Synonyms | |
| Description | FUNCTION: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. . |
| Accessions | ENST00000262053.8 [P18846-1] F8VYN3 F8VRN2 ENST00000549612.5 P18846 ENST00000551831.5 ENST00000552487.1 F8VYE5 ENST00000552510.5 F8VS03 |