ASCC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_0006307Biological processDNA alkylation repair
GO_0006355Biological processregulation of DNA-templated transcription
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0031594Cellular componentneuromuscular junction
GO_1990391Cellular componentDNA repair complex
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameASCC1
Protein nameActivating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)
Activating signal cointegrator 1 complex subunit 1
SynonymsCGI-18
DescriptionFUNCTION: Plays a role in DNA damage repair as component of the ASCC complex . Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation . In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction. .

AccessionsA0A5F9ZI10
E9PR40
A0A5F9ZHP1
H0YER2
ENST00000533958.1
ENST00000531048.5
Q8N9N2
ENST00000492502.2
ENST00000486689.6
ENST00000673599.1
ENST00000525286.6
A0A5K1VW55
E9PKM6
H0YE76
ENST00000526751.5
A0A5F9ZH79
ENST00000342444.8 [Q8N9N2-1]
ENST00000672940.1
A0A5F9ZI37
E9PQZ6
ENST00000672121.1
ENST00000317168.11
ENST00000317126.8 [Q8N9N2-2]
E9PL92
ENST00000672774.1
H0YCB3
ENST00000394915.7 [Q8N9N2-1]
E9PJM2
ENST00000524829.5
E9PM82
E9PQ44
ENST00000532011.5
H0YE79
ENST00000530394.5
ENST00000461369.6
ENST00000530461.5
ENST00000671788.1
A0A5F9ZGP6
ENST00000527593.5
ENST00000672957.1 [Q8N9N2-2]