ASAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0032580Cellular componentGolgi cisterna membrane
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameASAP2
Protein nameArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
SynonymsKIAA0400
DDEF2
DescriptionFUNCTION: Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. .

AccessionsENST00000281419.8 [O43150-1]
A0A286YFG8
ENST00000641030.1
O43150
ENST00000315273.4 [O43150-2]