Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 10 studies | 29% ± 11% | |
endothelial cell | 10 studies | 26% ± 9% | |
adipocyte | 6 studies | 25% ± 8% | |
glutamatergic neuron | 6 studies | 39% ± 20% | |
neuron | 4 studies | 30% ± 16% | |
Mueller cell | 4 studies | 49% ± 10% | |
basal cell | 4 studies | 35% ± 30% | |
respiratory goblet cell | 4 studies | 41% ± 19% | |
GABAergic neuron | 4 studies | 35% ± 15% | |
ionocyte | 3 studies | 29% ± 5% | |
epithelial cell | 3 studies | 45% ± 29% | |
mesothelial cell | 3 studies | 35% ± 13% | |
retina horizontal cell | 3 studies | 23% ± 8% | |
endothelial cell of lymphatic vessel | 3 studies | 22% ± 4% | |
hepatocyte | 3 studies | 32% ± 18% | |
oligodendrocyte precursor cell | 3 studies | 27% ± 8% | |
type I pneumocyte | 3 studies | 20% ± 3% | |
goblet cell | 3 studies | 47% ± 30% | |
mucus secreting cell | 3 studies | 50% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 3656.78 | 89 / 89 | 99% | 16.80 | 895 / 901 |
pancreas | 100% | 2705.01 | 328 / 328 | 93% | 8.31 | 165 / 178 |
esophagus | 97% | 1193.83 | 1398 / 1445 | 95% | 6.68 | 173 / 183 |
adrenal gland | 100% | 5598.00 | 258 / 258 | 87% | 6.89 | 199 / 230 |
breast | 100% | 1598.71 | 458 / 459 | 83% | 4.71 | 927 / 1118 |
thymus | 100% | 3030.24 | 651 / 653 | 78% | 5.62 | 469 / 605 |
uterus | 94% | 1214.61 | 159 / 170 | 82% | 5.28 | 375 / 459 |
ovary | 100% | 4618.97 | 180 / 180 | 74% | 3.47 | 319 / 430 |
stomach | 93% | 3750.89 | 334 / 359 | 81% | 3.93 | 231 / 286 |
lung | 90% | 963.33 | 523 / 578 | 81% | 5.02 | 936 / 1155 |
intestine | 63% | 425.04 | 604 / 966 | 87% | 4.45 | 461 / 527 |
liver | 80% | 712.32 | 180 / 226 | 68% | 3.86 | 275 / 406 |
prostate | 98% | 1251.36 | 240 / 245 | 47% | 1.67 | 236 / 502 |
bladder | 67% | 704.57 | 14 / 21 | 72% | 3.81 | 364 / 504 |
skin | 100% | 2948.31 | 1807 / 1809 | 38% | 1.75 | 178 / 472 |
tonsil | 0% | 0 | 0 / 0 | 100% | 11.67 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.41 | 1 / 1 |
adipose | 99% | 1310.34 | 1190 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 84% | 1492.78 | 1116 / 1335 | 0% | 0 | 0 / 0 |
spleen | 80% | 595.73 | 194 / 241 | 0% | 0 | 0 / 0 |
brain | 33% | 210.48 | 866 / 2642 | 11% | 0.36 | 76 / 705 |
heart | 11% | 60.11 | 96 / 861 | 0% | 0 | 0 / 0 |
muscle | 4% | 21.77 | 35 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 25.96 | 28 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0000902 | Biological process | cell morphogenesis |
GO_0048013 | Biological process | ephrin receptor signaling pathway |
GO_0060052 | Biological process | neurofilament cytoskeleton organization |
GO_0035023 | Biological process | regulation of Rho protein signal transduction |
GO_0021955 | Biological process | central nervous system neuron axonogenesis |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | ARHGEF28 |
Protein name | Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor) ARHGEF28 |
Synonyms | RGNEF KIAA1998 |
Description | FUNCTION: Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis (By similarity). . |
Accessions | ENST00000437974.5 [Q8N1W1-6] D6RAP0 Q8N1W1 A0A2X0U2G7 ENST00000426542.6 [Q8N1W1-1] ENST00000296799.8 [Q8N1W1-5] ENST00000296794.10 [Q8N1W1-4] ENST00000513042.7 [Q8N1W1-1] ENST00000509848.5 ENST00000512883.1 ENST00000545377.5 [Q8N1W1-6] D6RGZ3 |