ARAP3 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	15 studies	24% ± 6%	Explore
retina horizontal cell	4 studies	26% ± 4%	Explore
endothelial cell of lymphatic vessel	4 studies	27% ± 2%	Explore
capillary endothelial cell	3 studies	22% ± 3%	Explore
endothelial cell of vascular tree	3 studies	27% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ARAP3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	3420.10	21 / 21	97%	17.66	489 / 504
uterus	100%	4063.40	170 / 170	97%	17.04	443 / 459
esophagus	98%	1842.90	1423 / 1445	97%	16.82	178 / 183
lung	100%	6981.62	578 / 578	95%	11.18	1097 / 1155
stomach	99%	1483.91	355 / 359	95%	13.70	273 / 286
breast	100%	4488.12	459 / 459	94%	8.66	1047 / 1118
intestine	100%	1931.97	963 / 966	93%	12.08	491 / 527
thymus	100%	3867.64	653 / 653	92%	12.91	559 / 605
adrenal gland	100%	1942.77	258 / 258	90%	16.59	206 / 230
ovary	95%	1448.02	171 / 180	91%	12.01	393 / 430
prostate	100%	3668.18	245 / 245	86%	6.43	430 / 502
skin	89%	1087.61	1615 / 1809	94%	29.30	446 / 472
brain	82%	982.64	2178 / 2642	96%	15.21	678 / 705
kidney	100%	3637.51	89 / 89	74%	15.83	663 / 901
pancreas	44%	365.83	144 / 328	97%	16.10	173 / 178
liver	49%	451.62	110 / 226	60%	4.42	245 / 406
adipose	100%	4646.92	1204 / 1204	0%	0	0 / 0
heart	100%	3320.02	861 / 861	0%	0	0 / 0
spleen	100%	3733.61	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.30	1 / 1
blood vessel	99%	2068.93	1323 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	8.56	40 / 45
muscle	85%	792.28	681 / 803	0%	0	0 / 0
peripheral blood	80%	3643.20	741 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	64%	5.18	51 / 80
lymph node	0%	0	0 / 0	17%	0.87	5 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007165	Biological process	signal transduction
GO_0016192	Biological process	vesicle-mediated transport
GO_0007010	Biological process	cytoskeleton organization
GO_0001726	Cellular component	ruffle
GO_0005856	Cellular component	cytoskeleton
GO_0030027	Cellular component	lamellipodium
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005547	Molecular function	phosphatidylinositol-3,4,5-trisphosphate binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity
GO_0043325	Molecular function	phosphatidylinositol-3,4-bisphosphate binding

Gene name	ARAP3
Protein name	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 (Centaurin, delta 3, isoform CRA_b) Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) ARAP3 protein (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3) ARAP3 protein
Synonyms	CENTD3 hCG_1980706
Description	FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin. .
Accessions	ENST00000626478.2 Q8WWN8 G5E9Y3 ENST00000508305.5 ENST00000504448.1 Q96G49 Q05CH1 Q05CA7 ENST00000239440.9 [Q8WWN8-1] ENST00000513878.5 [Q8WWN8-2]

ARAP3 report