Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 19 studies | 25% ± 10% | |
non-classical monocyte | 16 studies | 30% ± 13% | |
classical monocyte | 15 studies | 26% ± 11% | |
monocyte | 12 studies | 24% ± 6% | |
microglial cell | 8 studies | 26% ± 10% | |
myeloid cell | 5 studies | 30% ± 13% | |
astrocyte | 4 studies | 26% ± 3% | |
alveolar macrophage | 4 studies | 28% ± 12% | |
endothelial cell | 3 studies | 18% ± 3% | |
epithelial cell | 3 studies | 21% ± 3% | |
intermediate monocyte | 3 studies | 33% ± 15% | |
type I pneumocyte | 3 studies | 19% ± 4% | |
oligodendrocyte | 3 studies | 23% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5460.52 | 1444 / 1445 | 100% | 34.85 | 183 / 183 |
thymus | 100% | 8266.75 | 653 / 653 | 100% | 53.06 | 604 / 605 |
breast | 100% | 5677.55 | 459 / 459 | 99% | 30.58 | 1111 / 1118 |
uterus | 100% | 7354.28 | 170 / 170 | 99% | 29.67 | 456 / 459 |
stomach | 100% | 4018.95 | 359 / 359 | 99% | 26.15 | 284 / 286 |
kidney | 100% | 6400.65 | 89 / 89 | 99% | 34.00 | 894 / 901 |
lung | 100% | 12201.09 | 578 / 578 | 99% | 33.87 | 1146 / 1155 |
ovary | 100% | 7981.49 | 180 / 180 | 99% | 30.89 | 426 / 430 |
intestine | 100% | 6115.39 | 966 / 966 | 99% | 26.39 | 522 / 527 |
bladder | 100% | 6109.76 | 21 / 21 | 99% | 31.62 | 499 / 504 |
prostate | 100% | 7103.24 | 245 / 245 | 99% | 23.96 | 497 / 502 |
skin | 100% | 5219.58 | 1808 / 1809 | 99% | 37.94 | 467 / 472 |
brain | 99% | 3542.54 | 2606 / 2642 | 100% | 33.45 | 703 / 705 |
pancreas | 98% | 3388.98 | 323 / 328 | 99% | 34.02 | 177 / 178 |
adrenal gland | 100% | 9356.84 | 258 / 258 | 98% | 27.37 | 225 / 230 |
liver | 99% | 3169.41 | 223 / 226 | 95% | 18.68 | 387 / 406 |
adipose | 100% | 6292.41 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 39.41 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 54.30 | 29 / 29 |
peripheral blood | 100% | 21034.62 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 17084.44 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 28.99 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.59 | 1 / 1 |
blood vessel | 99% | 4649.05 | 1328 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 4107.29 | 844 / 861 | 0% | 0 | 0 / 0 |
muscle | 81% | 1599.83 | 647 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001921 | Biological process | positive regulation of receptor recycling |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007165 | Biological process | signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0051491 | Biological process | positive regulation of filopodium assembly |
GO_0007015 | Biological process | actin filament organization |
GO_0008360 | Biological process | regulation of cell shape |
GO_0051497 | Biological process | negative regulation of stress fiber assembly |
GO_0005886 | Cellular component | plasma membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0032580 | Cellular component | Golgi cisterna membrane |
GO_0005547 | Molecular function | phosphatidylinositol-3,4,5-trisphosphate binding |
GO_0031702 | Molecular function | type 1 angiotensin receptor binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ARAP1 |
Protein name | ARAP1 protein ARAP1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
Synonyms | CENTD2 KIAA0782 |
Description | FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity). . |
Accessions | F5GWN4 A0A2X0SFK3 F8WBT0 ENST00000427971.6 ENST00000393609.8 [Q96P48-6] Q96P48 ENST00000536885.1 ENST00000393605.7 [Q96P48-1] ENST00000426523.5 ENST00000334211.12 [Q96P48-4] F5GWQ2 ENST00000429686.5 [Q96P48-7] E7EU13 B7ZMI2 ENST00000542596.5 ENST00000452383.2 H0YGD1 ENST00000359373.9 [Q96P48-3] |