APOBEC1 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	3 studies	23% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of APOBEC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	52%	162.69	505 / 966	80%	17.19	423 / 527
stomach	35%	12.42	126 / 359	69%	13.13	198 / 286
pancreas	3%	0.29	10 / 328	62%	16.98	111 / 178
esophagus	1%	0.27	9 / 1445	30%	4.78	54 / 183
bladder	0%	0	0 / 21	23%	4.46	118 / 504
lung	0%	0.03	1 / 578	17%	2.59	200 / 1155
uterus	1%	0.08	1 / 170	4%	0.50	18 / 459
kidney	3%	0.27	3 / 89	1%	0.02	5 / 901
breast	1%	0.90	5 / 459	1%	0.03	6 / 1118
adrenal gland	1%	0.05	2 / 258	0%	0	0 / 230
adipose	1%	0.06	9 / 1204	0%	0	0 / 0
liver	0%	0	0 / 226	1%	0.03	3 / 406
prostate	0%	0.02	1 / 245	0%	0	0 / 502
thymus	0%	0	0 / 653	0%	0.03	2 / 605
blood vessel	0%	0.02	3 / 1335	0%	0	0 / 0
heart	0%	0.01	1 / 861	0%	0	0 / 0
skin	0%	0.01	2 / 1809	0%	0	0 / 472
brain	0%	0.00	1 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
ovary	0%	0	0 / 180	0%	0	0 / 430
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042158	Biological process	lipoprotein biosynthetic process
GO_0006397	Biological process	mRNA processing
GO_0010332	Biological process	response to gamma radiation
GO_0048255	Biological process	mRNA stabilization
GO_0009972	Biological process	cytidine deamination
GO_0051649	Biological process	establishment of localization in cell
GO_0090209	Biological process	negative regulation of triglyceride metabolic process
GO_0016554	Biological process	cytidine to uridine editing
GO_2000623	Biological process	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO_0006641	Biological process	triglyceride metabolic process
GO_0016556	Biological process	mRNA modification
GO_0042953	Biological process	lipoprotein transport
GO_0006629	Biological process	lipid metabolic process
GO_0044029	Biological process	positive regulation of gene expression via chromosomal CpG island demethylation
GO_0042127	Biological process	regulation of cell population proliferation
GO_0030895	Cellular component	apolipoprotein B mRNA editing enzyme complex
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0045293	Cellular component	mRNA editing complex
GO_0005634	Cellular component	nucleus
GO_0004126	Molecular function	cytidine deaminase activity
GO_0035925	Molecular function	mRNA 3'-UTR AU-rich region binding
GO_0008270	Molecular function	zinc ion binding
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

Gene name	APOBEC1
Protein name	C->U-editing enzyme APOBEC-1 (EC 3.5.4.36) (mRNA(cytosine(6666)) deaminase 1) C->U-editing enzyme APOBEC-1 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic subunit 1) (APO1) (APOBEC-1) (Apolipoprotein B mRNA-editing enzyme 1) (EC 3.5.4.36) (HEPR) (mRNA(cytosine(6666)) deaminase 1) Apolipoprotein B mRNA editing enzyme catalytic subunit 1
Synonyms
Description	FUNCTION: Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs . Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA . Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA . May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (By similarity). .
Accessions	ENST00000229304.5 P41238 ENST00000467171.2 A0A0B4J232 Q4VB33

APOBEC1 report