Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 17 studies | 61% ± 18% | |
| glutamatergic neuron | 10 studies | 45% ± 17% | |
| neuron | 8 studies | 56% ± 23% | |
| GABAergic neuron | 8 studies | 34% ± 14% | |
| interneuron | 6 studies | 29% ± 10% | |
| oligodendrocyte precursor cell | 5 studies | 22% ± 9% | |
| pancreatic A cell | 4 studies | 61% ± 20% | |
| astrocyte | 4 studies | 24% ± 7% | |
| endothelial cell | 4 studies | 28% ± 12% | |
| OFF-bipolar cell | 4 studies | 27% ± 8% | |
| retinal ganglion cell | 4 studies | 55% ± 29% | |
| retina horizontal cell | 4 studies | 45% ± 20% | |
| pancreatic D cell | 3 studies | 48% ± 26% | |
| type B pancreatic cell | 3 studies | 56% ± 17% | |
| retinal bipolar neuron | 3 studies | 46% ± 16% | |
| ON-bipolar cell | 3 studies | 32% ± 10% | |
| amacrine cell | 3 studies | 46% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 34641.88 | 2640 / 2642 | 100% | 334.46 | 703 / 705 |
| pancreas | 72% | 2473.23 | 237 / 328 | 67% | 65.78 | 119 / 178 |
| adrenal gland | 12% | 616.02 | 31 / 258 | 81% | 581.18 | 187 / 230 |
| ovary | 0% | 0 | 0 / 180 | 64% | 39.00 | 275 / 430 |
| stomach | 39% | 1501.22 | 140 / 359 | 12% | 5.67 | 33 / 286 |
| uterus | 0% | 0 | 0 / 170 | 36% | 18.30 | 167 / 459 |
| breast | 0% | 0 | 0 / 459 | 26% | 13.21 | 290 / 1118 |
| skin | 0% | 2.65 | 2 / 1809 | 24% | 8.69 | 114 / 472 |
| lung | 0% | 0 | 0 / 578 | 19% | 6.18 | 219 / 1155 |
| esophagus | 0% | 1.56 | 1 / 1445 | 15% | 5.52 | 28 / 183 |
| liver | 0% | 0 | 0 / 226 | 12% | 6.12 | 47 / 406 |
| intestine | 0% | 2.72 | 1 / 966 | 9% | 5.75 | 48 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 3.12 | 4 / 45 |
| bladder | 0% | 0 | 0 / 21 | 9% | 4.18 | 43 / 504 |
| prostate | 0% | 0 | 0 / 245 | 6% | 2.14 | 31 / 502 |
| thymus | 0% | 0 | 0 / 653 | 6% | 1.23 | 36 / 605 |
| kidney | 0% | 0 | 0 / 89 | 6% | 1.87 | 51 / 901 |
| eye | 0% | 0 | 0 / 0 | 5% | 2.76 | 4 / 80 |
| blood vessel | 2% | 42.22 | 21 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 14.10 | 4 / 861 | 0% | 0 | 0 / 0 |
| adipose | 0% | 5.19 | 2 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006897 | Biological process | endocytosis |
| GO_0030900 | Biological process | forebrain development |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0007155 | Biological process | cell adhesion |
| GO_0180011 | Biological process | cytosolic mRNA polyadenylation |
| GO_0006417 | Biological process | regulation of translation |
| GO_0007409 | Biological process | axonogenesis |
| GO_0071874 | Biological process | cellular response to norepinephrine stimulus |
| GO_0007417 | Biological process | central nervous system development |
| GO_0006915 | Biological process | apoptotic process |
| GO_0106072 | Biological process | negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007399 | Biological process | nervous system development |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005604 | Cellular component | basement membrane |
| GO_0008201 | Molecular function | heparin binding |
| GO_0031696 | Molecular function | alpha-2C adrenergic receptor binding |
| GO_0046914 | Molecular function | transition metal ion binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0031694 | Molecular function | alpha-2A adrenergic receptor binding |
| GO_0031695 | Molecular function | alpha-2B adrenergic receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | APLP1 |
| Protein name | Amyloid beta precursor like protein 1 Amyloid beta precursor like protein 1 (cDNA FLJ56046, highly similar to Amyloid-like protein 1 (APLP)(APLP-1)) Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30] |
| Synonyms | |
| Description | FUNCTION: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. .; FUNCTION: The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis. . |
| Accessions | ENST00000221891.9 [P51693-2] ENST00000592316.1 ENST00000587274.1 ENST00000590561.5 P51693 S4R3U6 K7EMN4 ENST00000652533.1 [P51693-1] F5GZ08 ENST00000589743.5 K7EMS1 B7Z4G8 ENST00000586861.5 K7ELK0 ENST00000588808.5 K7EQJ4 ENST00000537454.6 |